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MetabolomicsDistinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones

INTRODUCTION: Prostatitis is likely to occur in younger or middle-aged men, while prostate cancer is likely to occur in older men. Although amino acids and lipids as biomarkers of prostate cancer have been examined using prostate cancer cell lines/tissues, no previous studies hav...

2020-11-04 | MTBLS2028 | MetaboLights
ProteomicsIdentification of Altered Proteins in the Plasma of Rats with Chronic Prostatic Inflammation Induced by Estradiol Benzoate and Sex Hormones
The cause of non-bacterial chronic prostatitis is unknown, yet its prevalence accounts for more than 90% of all prostatitis cases. Whole blood, plasma, and serum have been used to identify prostate cancer biomarkers; however, few studies have performed protein profiling to identify prostatitis bioma...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-10 | PXD024422 | Pride
Estradiol Proteomics Plasma Prostate Rats Testosterone Estradiol benzoate Chronic inflammation 
TranscriptomicsTranscription profiling of rat uterine myometrium -effect of estrogen
Uterine tissue is highly responsive to estrogen, which plays a mayor role in sympathetic innervation remodeling in myometrium; Microarrays were used to investigate which estrogen resposive myometrial proteins can be involved in innervation modulation Experiment Overall Design: Mature female rats wer...
ORGANISM(S): Rattus norvegicus 
2008-06-17 | E-GEOD-9117 | biostudies-arrayexpress
GenomicsGene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with Estradiol Benzoate, Estradiol and Testosterone
Gene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with Estradiol Benzoate, Estradiol and Testosterone
PRJNA608728 | ENA
TranscriptomicsPerinatal-Estrogen-Induced Changes in Gene Expression Related to Brain Sexual Differentiation in Mice
Sexual dimorphism of the behaviors or physiological functions in mammals is mainly due to the sex difference of the brain. The goal of this study is to identify genes mediating sexaul dimorphism of the brain. The large-scale analysis with microarray in the present study is an attempt to obtain the ...
ORGANISM(S): Mus musculus 
2014-06-07 | E-GEOD-47798 | biostudies-arrayexpress
GenomicsHomo sapiens
Estradiol benzoate treated HepG2.2.15 cells raw sequence reads
PRJNA827867 | ENA
TranscriptomicsGene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with Estradiol Benzoate, Estradiol and Testosterone
Using rat prostate disease models that Prins and colleagues have developed (Ho et al., 2006 - PMID: 16740699), the purpose of the study is to identify gene(s) for diagnosing early stage of prostate diseases and monitoring the development of prostate diseases. To identify the genes, we analyzed whole...
ORGANISM(S): Rattus norvegicus 
2020-08-17 | GSE145917 | GEO
TranscriptomicsEstrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries
Estrogen is a reproductive steroid hormone that has both beneficial and detrimental effects on the cardiovascular system. Selective estrogen receptor modulators (SERMs) exhibit partial estrogen agonist/antagonist activity in estrogen target tissues. Since we still have an incomplete picture of the ...
ORGANISM(S): Rattus norvegicus 
2011-07-06 | E-GEOD-23037 | biostudies-arrayexpress
GenomicsProtective effects of Ganoderma lucidum spores on estradiol benzoate-induced TEC apoptosis and compromised double-positive thymocyte development
Protective effects of Ganoderma lucidum spores on estradiol benzoate-induced TEC apoptosis and compromised double-positive thymocyte development
PRJNA1067641 | ENA
TranscriptomicsEffects of estradiol and growth hormone on liver transcriptome in hypothyroid-orquiectomized rats
E2 and GH are critical regulators of growth and intermediate metabolism in mammals. Hypothyroidism causes endocrine and metabolic disturbances in the liver with features that mimic deficiencies of E2 or GH signalling. In this work, we used the hypothyroid-orchiectomized (TXOX) adult rat model to eva...
ORGANISM(S): Rattus norvegicus 
2014-02-28 | E-GEOD-50014 | biostudies-arrayexpress
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