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TranscriptomicsEstradiol or Testosterone treated efferent duct and caput epididymis
The role of estrogen and testosterone in the regulation of gene expression in the proximal reproductive tract is not completely understood. To address this question, mice were treated with testosterone or estradiol and RNA from the efferent ducts and caput epididymis was processed and hybridized to...
ORGANISM(S): Mus musculus 
2009-12-30 | E-GEOD-17553 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse hypogonadal testis that had been pretreated with testosterone proprionate for 2 weeks then submitted to testosterone withdrawal
Analysis of the transcriptome of testes of hypogonadal mice that had been pretreated with testosterone proprionate for 2 weeks then submitted to testosterone withdrawal.
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-438 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response of red grouse to gastro-intestinal nematode parasites and testosterone
The effect of testosterone on red grouse response to the parasitic nematode Trichostrongylus tenuis.
ORGANISM(S): Lagopus lagopus scotica 
2010-12-07 | E-MEXP-2913 | biostudies-arrayexpress
TranscriptomicsGene expression data from gastrocnemius muscle (m.Gas) in young adult mice
This study examined the effects of castration and testosterone replacement on global differential gene transcription in the gastrocnemius muscle (m.Gas) in young adult mice over 14-days. Each of the 3 treatment groups was composed of 3 independent biological replicates, totaling 9 arrays. Equal amou...
ORGANISM(S): Mus musculus 
2009-06-08 | E-GEOD-16486 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer cell lines treated with testosterone and testosterone-BSA conjugate
The role of androgen in breast cancer development is not fully understood although androgen receptors (AR) have been identified in breast cancer clinical samples and cell lines. However the whole spectra of androgen actions cannot be accounted to the classic AR mode of action and the possible existe...
ORGANISM(S): Homo sapiens 
2009-11-16 | E-GEOD-18146 | biostudies-arrayexpress
GenomicsThe organizational effects of testosterone on brain DNA methylome
Analysis of DNA methylation in the bed nucleus of the stria terminalis/preoptic area and striatum in response to perinatal testosterone exposure. The hypothesis tested was that treatment of females with testosterone on the day of birth would lead to masculinization of the methylome in adulthood. The...
ORGANISM(S): Mus musculus domesticus 
2013-08-29 | E-GEOD-50218 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human skeletal muscle from Hiv-Infected Men experiencing weight loss treated with testosterone
Context: Although androgen treatment increases muscle mass in HIV-infected men, the underlying mechanisms are poorly understood. Analysis of genome-wide microarray data obtained from skeletal muscle biopsies can be used to profile androgen-regulated pathways. Objective: To identify genes and pathway...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-5106 | biostudies-arrayexpress
ClinicalPerioperative Testosterone Replacement Therapy in Sarcopenic Male Colorectal Cancer Patients
With increasing age and the additional impact from the bowel cancer and the chemotherapy and/ or radiotherapy it has been described that testosterone (a male hormone produced naturally in the body) levels are reduced. Testosterone has an impact on numerous body functions including the muscle mass an...
2729656 | ecrin-mdr-crc
TranscriptomicsTestosterone effects on the HVC transcriptome of adult female European robins (Erithacus rubecula)
Female European robins routinely sing during the winter season, a time when they defend feeding territories and also show elevated circulating testosterone levels. We used wild female European robins captured during fall to examine the effects of testosterone administration on the transcriptome of t...
ORGANISM(S): Erithacus rubecula 
2014-11-03 | E-GEOD-59203 | biostudies-arrayexpress
TranscriptomicsAnalysis of the placental tissue transcriptome from normal and testosterone treated rat pregnancy
Elevated testosterone levels increase maternal blood pressure and decrease uterine blood flow in pregnancy, resulting in abnormal perinatal outcomes. The placenta is the key in understanding the pathophysiological processes associated with pregnancy. The current study is designed to characterize the...
ORGANISM(S): Rattus norvegicus 
2015-04-20 | E-GEOD-61543 | biostudies-arrayexpress
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