Ethanol metabolism

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Transcriptomics (1413)
Unknown (1367)
Genomics (381)
Proteomics (278)
Metabolomics (189)
Models (49)
Methylation profiling (2)
Other (1)

Organisms

Mus musculus (301)
Homo sapiens (298)
Saccharomyces cerevisiae (194)
Arabidopsis thaliana (53)
Rattus norvegicus (35)
Drosophila melanogaster (26)
Streptomyces coelicolor (24)
Escherichia coli (23)
Mycobacterium tuberculosis (19)
Schizosaccharomyces pombe (13)
Thermus thermophilus HB8 (12)
Dictyostelium discoideum (12)
Staphylococcus aureus (11)
Caenorhabditis elegans (11)
Escherichia coli K-12 (11)
Sinorhizobium meliloti (9)
Oncorhynchus mykiss (8)
Candida albicans (8)
Listeria monocytogenes (7)
Oryza sativa (7)
Vitis vinifera (7)
Bos taurus (7)
Burkholderia cenocepacia (7)
Sus scrofa (7)
Rhizobium leguminosarum (6)
Pseudomonas putida (6)
Synechocystis sp. PCC 6803 (6)
Zea mays (5)
Bacillus subtilis (5)
Plasmodium falciparum (5)

Organisms

Mus musculus (59)
Saccharomyces cerevisiae (32)
Homo sapiens (24)
Escherichia coli (7)
Danio rerio (7)
Rattus norvegicus (6)
Nitratidesulfovibrio vulgaris str. Hildenborough (4)
Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 (4)
Acetivibrio thermocellus DSM 1313 (4)
Clostridium ljungdahlii (3)
Clostridium autoethanogenum (3)
Drosophila melanogaster (3)
Candida albicans (2)
Aspergillus nidulans (2)
Pseudomonas aeruginosa (2)
Clostridioides difficile (2)
Zymomonas mobilis (2)
Acetivibrio thermocellus ATCC 27405 (2)
Saccharum hybrid cultivar (2)
Oncorhynchus mykiss (2)
Vibrio halioticoli (1)
Vibrio sp. dhg (1)
Clostridium ljungdahlii DSM 13528 (1)
Clostridium beijerinckii NCIMB 8052 (1)
Candida albicans SC5314 (1)
Corynebacterium glutamicum ATCC 13032 (1)
Bacillus cereus ATCC 14579 (1)
Nakaseomyces glabratus (1)
Trypanosoma brucei (1)
Bacillus cereus (1)

Repository

biostudies-arrayexpress (1380)
ENA (288)
pride (253)
MetaboLights (178)
geo (132)
BioModels (45)
MassIVE (9)
jPOST (8)
MetabolomicsWorkbench (7)
iProX (4)
PAXDB (4)
EGA (3)
FAIRDOMHub (3)
GNPS (3)
Cell Collective (1)
PeptideAtlas (1)

Tissue

Cell culture (43)
Liver (18)
Brain (12)
Plant cell (10)
Epithelial cell (10)
Leaf (9)
Heart (8)
Blood plasma (8)
Permanent cell line cell (7)
Kidney (7)
Photosynthetic cell (6)
Bone marrow (5)
Cell suspension culture (4)
Whole body (4)
Blood (4)
Bacterial cells (3)
Mammary gland (3)
Skin (3)
Macrophage (3)
Stem cell (3)
Hepatocyte (3)
T cell (3)
Lung (2)
Muscle cell (2)
Pancreatic islet (2)
Breast cancer cell line (2)
Seed (2)
Blood platelet (2)
Plant (1)
Feces (1)

Disease

Breast cancer (10)
Normal (6)
Disease free (4)
Melanoma (3)
Lung cancer (3)
Alzheimer's disease (3)
Porphyria NOS (2)
Parkinson's disease (2)
Prostate adenocarcinoma (2)
Neuroblastoma (2)
Cardiovascular system disease (2)
Type 2 diabetes mellitus (2)
Colon cancer (2)
Acute leukemia (2)
Amyotrophic lateral sclerosis (1)
Myeloid neoplasm (1)
Low-stage neuroblastoma (1)
Embryonic lethal at day 8.5 to 9.5 (1)
Ischaemia reperfusion injury (1)
Malignant fibrous histiocytoma (1)
T-cell acute lymphoblastic leukemia (1)
Hypopituitary (1)
Short day torpor (1)
Chronic myelogenous leukemia (1)
Carcinoma (1)
Adenocarcinoma (1)
Patients with LF syndrome and SOS of stage II active disease (1)
Infection (1)
Cancer (1)
Fanconi-like syndrome (1)

Technology Type

Mass Spectrometry (259)
Shotgun proteomics (122)
Mass spectrometry (110)
Bottom-up proteomics (67)
NMR spectroscopy (37)
Data-independent acquisition (35)
Data-dependent acquisition (31)
Mass spectrometry assay (27)
Gel-based experiment (20)
SWATH MS (14)
Affinity purification coupled with mass spectrometry proteomics (12)
NMR spectroscopy assay (5)
Mass spectrometry imaging (5)
Top-down proteomics (5)
EI (4)
HDMSE (4)
ESI (2)
All-ion fragmentation (2)
DiaPASEF (2)
SRM/MRM (2)
Illumina HiSeq 2000 (1)
NMR (1)
Affinity proteomics (1)
MSE (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (21)
Illumina HiSeq 2000 (16)
Illumina HiSeq 2500 (15)
NextSeq 500 (13)
Illumina HiSeq 4000 (12)
Illumina NovaSeq X (6)
Illumina MiSeq (6)
Illumina HiSeq 1500 (6)
Element AVITI (5)
Affymetrix Fluidics Station 400 (5)
G2565BA DNA microarray scanner [Agilent] (4)
GenePix 4000A [Axon Instruments] (3)
BGISEQ-500 (3)
HiSeq X Ten (3)
Microcentrifuge (2)
Infors HT Multitron shaker (2)
Complete Genomics (2)
Axon GenePix 4000A scanning hardware (2)
GeneChip Scanner 3000 [Affymetrix] (2)
GenePix Professional 4200A [Axon Instruments] (2)
Chemostat (2)
418 [Affymetrix] (2)
Illumina Genome Analyzer II (2)
Axon GenePix 4000B scanning hardware (2)
NextSeq 2000 (2)
DNBSEQ-G400 (2)
Illumina HiSeq 1000 (2)
DNBSEQ-T7 (2)
NextSeq 550 (2)
Standard laboratory equipment for RNA library construction (1)

Publication Date

2010 (227)
2013 (183)
2014 (162)
2008 (138)
2012 (134)
2016 (116)
2011 (112)
2015 (110)
2026 (100)
2025 (100)
2024 (82)
2009 (75)
2022 (69)
2007 (64)
2023 (56)
2021 (53)
2020 (49)
2019 (49)
2017 (44)
2005 (30)
2018 (27)
2006 (24)
2004 (11)
2003 (1)

UNIPROT ID/AC

NCB5R_KLULA (2)
Q6CXC0_KLULA (2)
Q6CIC7_KLULA (2)
Q6CJ52_KLULA (2)
Q6CLA5_KLULA (2)
Q6CWG2_KLULA (2)
Q6CQK6_KLULA (2)
Q6CTI4_KLULA (2)
Q6CX25_KLULA (2)
DUT_KLULA (2)
Q6CY86_KLULA (2)
ENOPH_KLULA (2)
Q6CL72_KLULA (2)
Q6CJI8_KLULA (2)
Q6CTI3_KLULA (2)
Q6CWG1_KLULA (2)
Q6CKV1_KLULA (2)
Q6CL71_KLULA (2)
Q6CVU6_KLULA (2)
Q6CL09_KLULA (2)
END3_KLULA (2)
Q6CJZ3_KLULA (2)
Q6CNC4_KLULA (2)
Q6CTS6_KLULA (2)
Q6CU46_KLULA (2)
F2Z6C8_KLULA (2)
Q6CRQ6_KLULA (2)
PAN1_KLULA (2)
Q6CMG5_KLULA (2)
Q6CY88_KLULA (2)

CHEBI ID

CHEBI:16236 (68)
CHEBI:16761 (56)
CHEBI:15422 (53)
CHEBI:16908 (50)
CHEBI:15846 (46)
CHEBI:17306 (44)
CHEBI:15343 (34)
CHEBI:16526 (34)
CHEBI:15361 (34)
CHEBI:17835 (32)
CHEBI:17794 (32)
CHEBI:16001 (32)
CHEBI:17665 (32)
CHEBI:18021 (32)
CHEBI:36655 (31)
CHEBI:18385 (31)
CHEBI:16136 (31)
CHEBI:29985 (31)
CHEBI:12071 (31)
CHEBI:32364 (31)
CHEBI:29991 (31)
CHEBI:36208 (31)
CHEBI:17232 (31)
CHEBI:16189 (31)
CHEBI:16947 (31)
CHEBI:16265 (31)
CHEBI:16763 (31)
CHEBI:32814 (31)
CHEBI:15740 (31)
CHEBI:36242 (31)

Metabolite Name

Creatine (44)
Uracil (41)
Glycine (40)
Taurine (40)
Choline (36)
Creatinine (36)
Hypoxanthine (36)
Valine (33)
Betaine (31)
Adenine (31)
Tyrosine (30)
Proline (30)
Inosine (30)
Methionine (29)
Uridine (29)
Alanine (28)
Phenylalanine (28)
Asparagine (28)
Glycerol (27)
Ornithine (27)
Succinate (27)
Isoleucine (27)
Xanthine (27)
L-Proline (26)
Threonine (26)
L-Glutamine (26)
Glutamine (26)
L-Phenylalanine (26)
Leucine (25)
Glutamate (25)

First Public Date

2014 (83)
2026 (36)
2024 (29)
2025 (24)
2023 (23)
2021 (15)
2017 (14)
2022 (13)
2020 (13)
2019 (13)
2015 (8)
2013 (8)
2018 (5)
2016 (4)

Modelling Approach

Constraint-based model (8)
Ordinary differential equation model (5)

Lab affiliation

Microbial Evolution Laboratory, Centro de Astrobiologia (CSIC-INTA), 28850 Torrejón de Ardoz, Madrid, Spain (5)
Wageningen University (5)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (3)
Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland (2)
Department of Chemistry, National and Kapodistrian University of Athens, 15784 Zografou, Greece (2)
Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (2)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (2)
ErasmusMC Neurology Laboratory of clinical and cancer proteomics Rotterdam The Netherlands (2)
Australian Institute for Bioengineering and Nanotechnology, The University of Queensland (2)
Department of Glycobiology, Institute of Chemistry, Slovak Academy of Sciences (2)
IRCCS Istituto G Gaslini (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
Institute of Molecular Biology (IMB) (2)
Institute for Immunology, University Medical Center Mainz. Langenbeckstr. 1 55131 Mainz, Germany (1)
State Key Laboratory for Infectious Disease Prevention and Control, Prion disease department, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China (1)
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China; (1)
Instituto Superior de InvestigacionesBiológicas (INSIBIO), CONICET‐UNT, and Instituto de Biología “Dr. FranciscoD. Barbieri,” Facultad de Bioquímica, Química y Farmacia, UNT, San Miguel de Tucumán, Argentina (1)
Center for Tuberculosis Control of Guangdong Province (1)
Department of Biochemistry and Molecular Biology and Agricultural Chemistry and Soil science University of Alicante SPAIN (1)
College of plant protection, Southwest University, China (1)
Institute of Anatomy Christian-Albrechts-University Kiel, Kiel, Germany (1)
Department of Rehabilitation Medicine, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China (1)
Proteomics mass spectrometry core facility, Central Science Laboratory, University of Tasmania, Australia (1)
1 Department of Biological Sciences, College of Arts and Sciences, University of North Texas, Denton, TX 2 Advanced Environmental Research Institute (AERI), University of North Texas, Denton, TX (1)
Professor University Research Chair in Integrative Mitochondrial Biology Interdisciplinary School of Health Sciences, Faculty of Health Sciences University of Ottawa RGN building, 451 Smyth Road, Ottawa, ON K1H 8M5 Canada (1)
Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA (1)
Genetics and Genomic Sciences (1)
Bioanalytical Mass Spectrometry Group, Max-Planck-Institute for Multidisciplinary Sciences, Germany; Bioanalytics, Department of Clinical Chemistry, University Medical Center Göttingen, Germany (1)
"Philip Morris R&D, Neuchatel, Switzerland" (1)
Saarland University Preclinical Center for Molecular Signalling (PZMS) Institute of Medical Biochemistry and Molecular Biology (1)

IsPrivate

False (45)

Model Flag

Non Kinetic (37)

Submitter Keywords

FROG (2)

Classification

bacteria (28)
fungi (7)
protozoa (1)

Modification

4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (950)
RNA-seq of coding RNA (151)
ChIP-seq (60)
Unknown experiment type (29)
RNA-seq of non coding RNA (22)
Other (21)
ChIP-chip by tiling array (18)
Methylation profiling by array (17)
Comparative genomic hybridization by array (16)
ChIP-chip by array (15)
Methylation profiling by high throughput sequencing (14)
DNA-seq (11)
Transcription profiling by tiling array (10)
RNA-seq of total RNA (10)
CUT&RUN (4)
Cell line - High-throughput sequencing (3)
Genotyping by array (3)
Animal - High-throughput sequencing (2)
MicroRNA profiling by array (2)
FAIRE-seq (1)
Transcription profiling by SAGE (1)
Metabolomic profiling (1)
MNase-seq (1)
Two-color microarray (1)
MeDIP-seq (1)
Animal - One-color microarray (1)
Human - High-throughput sequencing (1)
Translation profiling (1)
High-throughput sequencing (1)
RNAi profiling by array (1)

Release Date

2010 (237)
2013 (221)
2014 (190)
2012 (154)
2015 (151)
2025 (150)
2022 (147)
2008 (147)
2024 (140)
2021 (133)
2011 (133)
2023 (131)
2016 (128)
2020 (119)
2019 (115)
2018 (97)
2009 (85)
2017 (72)
2007 (71)
2026 (39)
2006 (30)
2005 (30)
2004 (16)
2003 (3)
2001 (3)
1998 (2)
2002 (1)
1999 (1)
1990 (1)

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Mechanism of Hepatotoxicity Induced by Ethanol Extract of Emilia sonchifolia (L.) DC Revealed by Proteomics and Metabolomics

Objective: Hepatotoxicity has been reported for Emilia sonchifolia (L.) DC (Emilia sonchifolia). The plant material is typically prepared using two extraction methods for practical application: water extraction and ethanol extraction. However, our previous research only investigated its wate...

2025-10-30 | MTBLS13237 | MetaboLights

Molecular Docking and Dynamic Study of Ethanol Extract of Citrus sinensis as Keap-1 and NMDA inhibitor in Brain Injury

Traumatic brain injury is a significant cause of mortality in young adults and disability in all age groups. Secondary injury involving various processes such as oxidative stress, which induced neuronal apoptosis, ensued afterward. This study aimed to analyze the active compounds of Citrus sinens...

2023-01-02 | MTBLS5785 | MetaboLights

Mung bean (Vigna radiata L.) ethanol extracts alleviate alcoholic liver injury with modulation of gut microbiota and spermidine elevation

The pathophysiology of alcoholic-associated liver disease (ALD) is multifaceted. Utilizing the gut-liver axis framework and integrated multi-omics approaches, this study systematically evaluated the therapeutic potential of mung bean (Vigna radiata L.) ethanol extracts (MBE) in ALD, and its...

2025-10-10 | MTBLS13109 | MetaboLights

Multi-omics analysis reveals the modulatory effects of Moringa oleifera ethanol extract on gut microbiota and metabolic profiles in broilers

The overuse of antimicrobial growth promoters (AGPs) in poultry farming has raised global concerns about antimicrobial resistance and food safety, prompting the search for effective natural alternatives. Moringa is rich in bioactive compounds with antimicrobial and immunomodulatory properties; ho...

2026-08-04 | MTBLS15049 | MetaboLights

Systems Biology Analysis of Zymomonas mobilis ZM4 Ethanol Stress Responses

Background Zymomonas mobilis ZM4 is a capable ethanologenic bacterium with high ethanol productivity and ethanol tolerance. Previous studies indicated that several stress-related proteins and changes in the ZM4 membrane lipid composition may contribute to ethanol tolerance. However, the molecular m...

ORGANISM(S): Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821

2013-09-04 | E-GEOD-21165 | biostudies-arrayexpress

Microarray characterization of gene expression changes in blood during acute ethanol exposure

As part of the civil aviation safety program to define the adverse effects of ethanol on flying performance, we present results of our DNA microarray analysis of samples from a timecourse study of individuals given ethanol orally, and then evaluated by breathalyzer to monitor blood alcohol content (...

ORGANISM(S): Homo sapiens

2013-07-25 | E-GEOD-20489 | biostudies-arrayexpress

Postnatal Growth Restriction and Gene Expression Changes in a Mouse Model of Fetal Alcohol Syndrome (Liver)

Growth restriction, craniofacial dysmorphology and central nervous system defects are the main diagnostic features of fetal alcohol syndrome. Studies in humans and mice have reported that the growth restriction can be prenatal and/or postnatal, but the underlying mechanisms remain unknown. We recen...

ORGANISM(S): Mus musculus

2010-09-30 | E-GEOD-23106 | biostudies-arrayexpress

The molecular response of Clostridium thermocellum ATCC 27405 to ethanol shock

Clostridium thermocellum is a Gram-positive, anaerobic, thermophilic bacterium that ferments cellulose into ethanol. It is a candidate industrial consolidated bioprocess (CBP) biocatalyst for lignocellulosic bioethanol production. However, C. thermocellum is relatively sensitive to ethanol compared ...

ORGANISM(S): Clostridium thermocellum ATCC 27405

2012-08-16 | E-GEOD-25236 | biostudies-arrayexpress

Postnatal Growth Restriction and Gene Expression Changes in a Mouse Model of Fetal Alcohol Syndrome (Kidney)

ORGANISM(S): Mus musculus

2010-10-01 | E-GEOD-23105 | biostudies-arrayexpress

Comparison of the transcriptome of the ethanol adapted yeast and control at 10% ethanol

In this study, using DNA microarray analysis, we compared the comprehensive expression profiles of two yeast trains, i.e, the previously obtained ethanol-adapted yeast strain and the parental strain as control (FY834), under the ethanol stress condition (YPD medium contained 10% ethanol). As a resul...

ORGANISM(S): Saccharomyces cerevisiae

2010-05-15 | E-GEOD-13757 | biostudies-arrayexpress

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