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MetabolomicsMulti-omics reveals the protective mechanisms of Gastrodia elata ethyl acetate extract in vascular dementia

Objective: This study aimed to investigate the ameliorative effect of the ethyl acetate extract of Gastrodia elata (EEGE) on vascular dementia (VD) and its underlying mechanisms. 

Methods: A VD rat model was established using the two-vessel occlusion method, while an in vitro cerebral ...

2026-01-15 | MTBLS13695 | MetaboLights
ProteomicsArabidopsis thaliana peptide SP2 and ethyl acetate extraction clean up.
The success of bottom-up proteomic analysis frequently depends on the efficient removal of contaminants from protein or peptide samples before LC-MS/MS. For a peptide clean-up workflow, the single-pot solid-phase-enhanced peptide sample preparation on carboxylate-modified paramagnetic beads (termed ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-01-03 | PXD045031 | Pride
Arabidopsis thaliana Peptide clean-up Ethyl acetate extraction Sp2 Polyethylene glycol Sodium dodecyl sulfate Magnetic beads Lc-ms/ms 
MetabolomicsComparative metabolomics of MCF-7 breast cancer cells using different extraction solvents assessed by mass spectroscopy
Not available
ORGANISM(S): Homo sapiens 
ST001265 | MetabolomicsWorkbench
TranscriptomicsEffect of Medroxyprogesterone Acetate on Transcript Profile of Human Pregnant Myometrium
Context: Progesterone is important physiologically and therapeutically to maintain uterine quiescence during pregnancy. It acts in part through controlling myometrial gene expression. Objective: To use expression microarray and qRT-PCR validation to determine the changes in gene expression induced ...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-GEOD-22961 | biostudies-arrayexpress
TranscriptomicsDifferential effects of progesterone and medroxyprogesterone acetate on normal breast cells
Comparison between the effects of progesterone (P4) and medroxyprogesterone acetate (MPA) combined to estradiol (E2) on gene expression in normal breast cells to provide insight on their possible different impact on breast cancer risk in vivo. Total RNA obtained from cultures of normal human breast ...
ORGANISM(S): Homo sapiens 
2011-05-30 | E-GEOD-23500 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type G. sulfurreducens DL1 strain and mutant delta-sfrAB::kan, acetate-adapted strain using fumarate as an electron acceptor
1. Summary: SfrAB, the soluble ferric reductase of Geobacter sulfurreducens, is a two subunit complex that can catalyze the NADPH-dependent reduction of chelated Fe(III) and is encoded in a two gene cluster in which the sfrB gene (GSU_0510) is 126 bp upstream of the sfrA gene (GSU_0509)[Kaufmann an...
ORGANISM(S): Geobacter sulfurreducens 
2008-01-03 | E-TIGR-130 | biostudies-arrayexpress
UnknownAutomated micro-solid-phase extraction clean-up and gas chromatography-tandem mass spectrometry analysis of pesticides in foods extracted with ethyl acetate.
Not available
S-EPMC10766720 | biostudies-literature
ProteomicsUnraveling the mechanism of ethyl acetate extract from Prismatomeris connata Y. Z. Ruan root in treating pulmonary fibrosis: insights from bioinformatics, network pharmacology, and experimental validation
Pulmonary fibrosis (PF) is a terminal lung disease characterized by fibroblast proliferation, accumulation of extracellular matrix accumulation, inflammatory damage, and tissue structure destruction. The pathogenesis of this disease, especiallyparticularly idiopathic pulmonary fibrosis (IPF), is sti...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-07 | PXD048007 | Pride
Inflammation/wound healing balance Macrophages polarization Pulmonary fibrosis Ethyl acetate extract Prismatomeris connata y. z. ruan 
UnknownBenchmarking of Two Peptide Clean-Up Protocols: SP2 and Ethyl Acetate Extraction for Sodium Dodecyl Sulfate or Polyethylene Glycol Removal from Plant Samples before LC-MS/MS.
Not available
S-EPMC10743447 | biostudies-literature
UnknownBioactivity and phenolics profile of aqueous and ethyl acetate extracts of Satureja kitaibelii Wierzb. ex Heuff. obtained by ultrasound-assisted extraction.
Not available
S-EPMC9731972 | biostudies-literature
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