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TranscriptomicsSigma(M) regulated genes under antibiotic stress (vancomycin)
Abstract of associated manuscript: The Bacillus subtilis extracytoplasmic function (ECF) sigma(M) factor is activated by cell envelope stress elicited by antibiotics, and by acid, heat, ethanol and superoxide stresses. Here, we have used several complementary approaches to identify genes controlled ...
ORGANISM(S): Bacillus subtilis 
2010-05-15 | E-GEOD-13820 | biostudies-arrayexpress
TranscriptomicsIsw2 and Ume6 ChIP-chip in transcription factor deletion (M-NM-^Tume6, M-NM-^Tnrg1, M-NM-^Tcin5, and M-NM-^Tsok2) and DNA-looping deficient (sua7-1) cells
The sequence-specific transcription factors Ume6, Nrg1, Cin5, and Sok2 and the general transcription factor TFIIB mediate the genome-wide targeting of the ATP-dependent chromatin remodeling enzyme Isw2. At least two biological replicates comparing Isw2-ChIP (Isw2-K215R ChIP DNA competitively hybridi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-14 | E-GEOD-39542 | biostudies-arrayexpress
TranscriptomicsDual RNA-seq of M. tuberculosis H37Rv infecting macrophage-like THP-1 cells during 48h
Transcriptional changes during early infection of macrophage-like THP-1 cell line with pathogenic bacterium Mycobacterium tuberculosis. RNAseq samples were taken at 0h (THP-1 cells growing in the RPMI medium), and after 4h, 24h and 48h post infection. Bacterial enrichment was performed to increase t...
ORGANISM(S): Homo sapiens 
2017-08-01 | E-MTAB-5287 | biostudies-arrayexpress
TranscriptomicsGain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome
This SuperSeries is composed of the following subset Series: GSE27331: Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with adverse clinical outcome [penn1Mb data] GSE27332: Gain of the oncostatin M receptor in cervical squamous cell carcinoma is associated with a...
ORGANISM(S): Homo sapiens 
2011-02-16 | E-GEOD-27333 | biostudies-arrayexpress
TranscriptomicsChronic alcohol consumption from adolescence-to-adulthood in mice M-bM-^@M-^T Effect on gene expression in the hypothalamus
We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice, and analyzed the alcohol effect on both behavioral and hypothalamic gene expression changes. We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice. Before chroni...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-42770 | biostudies-arrayexpress
TranscriptomicsRole of the extracytoplasmic-function sigma Factor sigmaH in Mycobacterium tuberculosis global gene expression
Like other bacterial species, Mycobacterium tuberculosis has multiple sigma (s) factors encoded in its genome. In previously published work, we and others have shown that mutations in some of these transcriptional activators render M. tuberculosis sensitive to various environmental stresses and, in ...
ORGANISM(S): Mycobacterium tuberculosis 
2007-08-03 | E-GEOD-8689 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of M. tuberculosis constitutively expressing the transcriptional regulator DosR (Rv3133c).
Background: Conflicting results have been reported about the role of the two-component sensor and transcriptional regulator DosS/DosR, controlling the expression of the dormancy DosR regulon, for in vivo virulence of M. tuberculosis. Here, we have used a new approach to further analyze the relevance...
ORGANISM(S): Mycobacterium tuberculosis 
2012-06-12 | E-GEOD-19838 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast with deletion or overexpression of ste11 and changes in gene expression after nitrogen starvation of h plus, h minus, h90fus1 and h90ste11 cells to investigate control of gene expression during early sexual differentiation
Fission yeast cells belong to one of two specialized cell types, M or P. Specific environmental conditions trigger sexual differentiation, which leads to an internal program starting with pheromone signalling between M and P cells, followed by mating, meiosis and sporulation. The initial steps of ...
ORGANISM(S): Schizosaccharomyces pombe 
2006-09-22 | E-TABM-139 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat liver to investigate ethanol induced hepatic gene expression changes during gestation
The specific role of nutritional status during gestation in exacerbating or mitigating fetal toxicity of ethanol (EtOH) remains unclear. We used an intragastric infusion model (Total enteral nutrition, TEN) to appropriately control for dietary EtOH consumption and caloric intake. Time impregnated fe...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3740 | biostudies-arrayexpress
UnknownImproved Efficacy of Synthesizing *MIII-Labeled DOTA Complexes in Binary Mixtures of Water and Organic Solvents. A Combined Radio- and Physicochemical Study.
Not available
S-EPMC6121814 | biostudies-literature
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