Sort   by:  
 Page size 
TranscriptomicsExpression data from the basolateral amygdala of Long-Evans rats with a history of limited intermittent sucrose snacks
To study the molecular mediators of naturally rewarding effects of palatable food we used a model of palatable “snacking” (Ulrich-Lai et al., 2007) in which rats are given chronic, brief access to a limited amount of sucrose solution (30%). Single housed, male Long-Evans rats (250g) (n=12 per...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20344 | biostudies-arrayexpress
UnknownThermodynamic linkage between calmodulin domains binding calcium and contiguous sites in the C-terminal tail of Ca(V)1.2.
Not available
S-EPMC3340011 | biostudies-literature
TranscriptomicsTranscriptome analysis of N,C and P limitations in S. coelicolor
A genome-wide transcriptomic analysis of the response of the model streptomycete Streptomyces coelicolor A3(2) M145 to fermentor culture in Modified Evans Media limited, respectively, for nitrogen, phosphate and carbon
ORGANISM(S): Streptomyces coelicolor A3(2) 
2011-05-01 | E-MAXD-59 | biostudies-arrayexpress
TranscriptomicsMicro-RNAs in Adult Long-Evans (Turku/AB) Rat Liver are Refractory to 96 Hours Dioxin Treatment
Dioxin-like chemicals are well-known for their ability to upregulate expression of numerous genes via the AH receptor (AHR). However, recent transcriptomic analyses in several laboratories indicate that dioxin-like chemicals or AHR genotype itself also can downregulate levels of mRNAs encoded by nu...
ORGANISM(S): Rattus norvegicus 
2007-08-14 | E-GEOD-8469 | biostudies-arrayexpress
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
TranscriptomicsTranscription profiling of rat liver display strain-specific, hereditary and AHR-Dependent Components
Background; The rat is a major model organism in toxicogenomics and pharmacogenomics, and the use of steady-state hepatic mRNA levels to predict and understand drug toxicity and mechanism is well-established. Surprisingly, the inter- and intra-strain variability of rat mRNA expression has not been e...
ORGANISM(S): Rattus norvegicus 
2009-11-28 | E-GEOD-10448 | biostudies-arrayexpress
MetabolomicsA conserved metabolic signature associated with response to fast-acting antimalarial agents

Characterizing the mode of action of antimalarial compounds that emerge from high-throughput phenotypic screens is central to understanding how parasite resistance to these drugs can emerge. Here, we have employed untargeted metabolomics to inform on the mechanism of action of antimalarial leads ...

2023-09-27 | MTBLS6580 | MetaboLights
TranscriptomicsCardiac miRNA expression changes induced by prediabetes
The aim of the experiment was the analysis of key molecular changes with an unbiased, transcriptomics-based approach in a prediabetes model. Small RNA sequencing analysis was applied to explore the expression changes resulted high-fat chow (supplemented with 40% lard) diet for 21 weeks and a single ...
ORGANISM(S): Rattus norvegicus 
2020-04-24 | E-MTAB-8204 | biostudies-arrayexpress
ProteomicsA super-enhancer regulated RNA-binding protein cascade drives pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy in need of new therapeutic options. Using an unbiased analysis of super-enhancers (SEs) as sentinels of core genes involved in cell-specific function, we uncover a druggable SE-mediated RNA-binding protein (RBP) cascade that supports PDA...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-15 | PXD030423 | Pride
Prmt1 Rna-binding protein Pancreatic cancer Super-enhancers Tumor growth 
UnknownTargeted cell imaging properties of a deep red luminescent iridium(iii) complex conjugated with a c-Myc signal peptide.
Not available
S-EPMC7069228 | biostudies-literature
Sort   by:  
 Page size