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The mechanism of cardiotoxicity induced by evodiamine and matrine was revealed by epitranscriptomics
Evodiamine (Evo), a kind of alkaloid mostly extracted from Tetradium ruticarpum, which has many pharmacological functions, such as antidiarrheal, antiemetic, and antiulcer effects. In this study, the effects of Evo were investigated in DSS-induced ulcerative colitis (UC) mice and C57BL/6-ApcMinC/Gpt...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD027745 | Pride
By using epitranscriptomics, the mechanism of cardiotoxicity induced by evodiamine and matrine was discovered. Experimental findings indicated that evodiamine and matrine altered m6A levels within the cells.
ORGANISM(S): Homo sapiens 
2024-08-20 | GSE274753 | GEO
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