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ProteomicsDynamic proteomic profiling of extra-embryonic endoderm differentiation in mouse embryonic stem cells
During mammalian pre-implantation development, the cells of the blastocyst’s inner cell mass differentiate into the epiblast and primitive endoderm lineages, which give rise to the fetus and extra-embryonic tissues, respectively. Extra-embryonic endoderm differentiation can be modeled in vitro by in...
ORGANISM(S): Mus musculus (Mouse) 
2015-06-13 | PXD001901 | Pride
Extra-embryonic endoderm (xen) stem cells Differentiation Tandem mass tags (tmt) Quantitative proteomics Pluripotency 
TranscriptomicsRegulation of extraembryonic endoderm stem cell differentiation by Nodal and EGF-CFC signaling
The signaling pathway for Nodal, a ligand of the transforming growth factor-beta (TGF-beta) superfamily, plays a central role in regulating the maintenance and/or differentiation of stem cell types that can be derived from the peri-implantation mouse embryo. Extraembryonic endoderm stem (XEN) cells ...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-23675 | biostudies-arrayexpress
GenomicsDerivation and characterization of chimera-competent eXtra-Embryonic eNdoderm (XEN) cells from pig blastocysts
Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm (XEN) cells from pig blastocysts
PRJNA526553 | ENA
TranscriptomicsTranscription profiling of mouse ES cells versus XEN cells
Comparison of mouse ES cells and three different XEN cell cultures. Three XEN cell cultures: Two different strains (IM8A1 is PO, and XEN1-3 is ICR). And two different culture conditions (IM8A1-I versus IM8A1-II). Three biological replicates of XEN cell RNA were submitted to the Centre for Applied Ge...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2204 | biostudies-arrayexpress
UnknownConversion from mouse embryonic to extra-embryonic endoderm stem cells reveals distinct differentiation capacities of pluripotent stem cell states.
Not available
S-EPMC3403099 | biostudies-literature
UnknownRegulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling.
Not available
S-EPMC3160087 | biostudies-literature
UnknownDerivation of Porcine Extra-Embryonic Endoderm Cell Lines Reveals Distinct Signaling Pathway and Multipotency States.
Not available
S-EPMC8657774 | biostudies-literature
TranscriptomicsA XEN-like state bridges somatic cells to pluripotency during chemical reprogramming
Pluripotent stem cells can be generated from somatic cells by using pure chemicals.However, the cell fate dynamics and molecular events that occur during the chemical reprogramming process remain unclear. In this study, we found that the chemical reprogramming process requires the early formation of...
ORGANISM(S): Mus musculus 
2015-12-09 | E-GEOD-73631 | biostudies-arrayexpress
UnknownA pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression.
Not available
S-EPMC9534490 | biostudies-literature
TranscriptomicsConversion of mES to cXEN cells
The inner cell mass of the mouse pre-implantation blastocyst is comprised of epiblast progenitor and primitive endoderm cells of which cognate embryonic (mESCs) or extra-embryonic (XEN) stem cell lines can be derived. Importantly, each stem cell type retains the defining properties and lineage restr...
ORGANISM(S): Mus musculus 
2012-06-04 | E-GEOD-38477 | biostudies-arrayexpress
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