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TranscriptomicsSharkey trophoblast
Transcriptional profiling comparison of human primary villous trophoblast and extra-villous trophoblast (VT and EVT respectively) cells, isolated from the placenta at 8 to 12 weeks gestation, with complimentary transcriptional profiling of choriocarcinoma cell lines JEG-3 and JAR. Based on phenotypi...
ORGANISM(S): Homo sapiens 
2011-04-28 | E-MTAB-429 | biostudies-arrayexpress
ProteomicsAn integrated proteome and phospho-proteome approach to study BPA toxicity on placenta.
The environmental exposure of various Endocrine disrupting chemicals (EDCs) like Bisphenol-A (BPA), can affect human health by inducing hormonal imbalance important for physiological homeostasis. Pregnant females are more susceptible for BPA mediated toxicity. BPA can reach maternal circulation by i...
ORGANISM(S): Homo sapiens (Human) 
2026-07-14 | PXD074780 | Pride
Bisphenol-a Placenta Extra-villous trophoblast Zenoswath Ecotoxico-proteomics Phosphoproteome 
ProteomicsAn integrated proteome and phospho-proteome approach to study BPA toxicity on placenta.
The environmental exposure of various Endocrine disrupting chemicals (EDCs) like Bisphenol-A (BPA), can affect human health by inducing hormonal imbalance important for physiological homeostasis. Pregnant females are more susceptible for BPA mediated toxicity. BPA can reach maternal circulation by i...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-07-14 | PXD080006 | Pride
Bisphenol-a Placenta Extra-villous trophoblast Hr-mrm Targeted proteomics Ecotoxico-proteomics 
ProteomicsTargets of anti-trophoblast antibodies
Background: Our former study demonstrated that anti-trophoblast antibodies (ATAB) are more prevalent in the sera of patients with unexplained recurrent miscarriages (uRM), and the detection of ATAB is restricted to binding to JEG-3 cells and the quantification by flow cytometry. We further proved th...
ORGANISM(S): Homo sapiens (Human) 
2019-03-05 | PXD012478 | Pride
Unexplained recurrent miscarriages / anti-trophoblast antibodies / jeg-3 cells / anti-α-enolase antibodies 
UnknownEstablishment and characterization of a new human first trimester Trophoblast cell line, AL07.
Not available
S-EPMC8237240 | biostudies-literature
GenomicsDecidual natural killer cells promote extravillus trophoblast developmental pathways: evidence from trophoblast organoid co-cultures
Decidual natural killer cells promote extravillus trophoblast developmental pathways: evidence from trophoblast organoid co-cultures
PRJNA1137979 | ENA
TranscriptomicsDecidual natural killer cells promote extravillus trophoblast developmental pathways: evidence from trophoblast organoid co-cultures
The placenta an essential extra-embryonic organ that supports the fetus throughout gestation. The interactions between the placenta and the maternal immune system during the first trimester have not been completely characterized, despite their close physical association and hem-allogeneic relationsh...
ORGANISM(S): Homo sapiens 
2024-08-31 | GSE272695 | GEO
TranscriptomicsActivation of the interferon pathway in trophoblast cells infected with SARS-CoV-2
Infection with SARS-CoV-2 in pregnancy has been associated with poor maternal and neonatal outcomes and placental defects. The placenta, which acts as a physical and immunological barrier at the maternal/fetal interface, is not established until the end of the first trimester. Therefore, localized v...
ORGANISM(S): Homo sapiens 
2023-10-14 | GSE216484 | GEO
UnknownBreast Cancer Resistance Protein (BCRP/ABCG2) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral Infection.
Not available
S-EPMC6829363 | biostudies-literature
UnknownRole of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis.
Not available
S-EPMC8670385 | biostudies-literature
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