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ProteomicsDeep Exploration of the Immunopeptidome of a Pancreatic Cancer Cell Line Panc1: Implications for Clinical Immunopeptidomics and Immunotherapy (SWATH-DIA datasets)
Pancreatic ductal adenocarcinoma (PDAC), with its devastating prognosis and limited treatment options, necessitates innovative therapeutic strategies. T-cell-based immunotherapy has shown promise for various cancers, including PDAC. Thus, a comprehensive understanding of the HLA-peptidome in PDAC is...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD054417 | Pride
Tumor-associated antigens Hla Variable window zenoswath dia Pancreatic cancer Immunopeptidome Pdac 
ProteomicsDeep Exploration of the Immunopeptidome of a Pancreatic Cancer Cell Line Panc1: Implications for Clinical Immunopeptidomics and Immunotherapy (DDA datasets)
Pancreatic ductal adenocarcinoma (PDAC), with its devastating prognosis and limited treatment options, necessitates innovative therapeutic strategies. T-cell-based immunotherapy has shown promise for various cancers, including PDAC. Thus, a comprehensive understanding of the HLA-peptidome in PDAC is...
ORGANISM(S): Homo sapiens (Human) 
2025-07-14 | PXD054360 | Pride
Tumor-associated antigens Hla Variable window zenoswath dia Pancreatic cancer Immunopeptidome Pdac 
ProteomicsProteomic charaterization of GPX1 depletion in sarcoma models
The sarcomagenic process initiates upon the tumoral transformation of mesenchymal stromal/stem cell (MSCs) or MSC-derived cell types. Experimental evidence also supports that sarcoma evolution is in part driven by the emergence of subpopulations of cancer stem cells (CSCs) after the accumulation of ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD052595 | Pride
Human Sarcoma Cscs Gpx1 
ProteomicsEstablishment of a murine model of beta-parvalbumin-induced fish allergy and proteomic profiling of immune cell activation using DIA-based ZenoSWATH-MS
Food allergy is an immune-mediated condition caused by hypersensitivity to food allergens, with fish allergens, particularly beta-parvalbumins (beta-PRVBs), being the most significant. While the only effective treatment is avoidance of the food allergen, the intracellular mechanisms of immune activa...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-05-13 | MSV000097859 | MassIVE
ProteomicsProteomic Analysis of ROCK Inhibitor-treated ARPE-19 Cells
Rho-associated protein kinase (ROCK) inhibitors are highly present in different ocular tissues, and upregulation of ROCK pathway has been shown related to the pathogenesis of multiple ocular disorders, including glaucoma, diabetic retinopathy and age-related macular degeneration (AMD). However, the ...
ORGANISM(S): Homo sapiens (Human) 
2024-12-04 | PXD051479 | Pride
Autophagy Rpe Oneomics Rock inhibitor Zeno swath 
UnknownDeep Exploration of the Immunopeptidome of a Pancreatic Cancer Cell Line: Implications for Clinical Immunopeptidomics and Immunotherapy.
Not available
S-EPMC12362687 | biostudies-literature
ProteomicsSWATH-MS-Based landscape of serum proteins in acute respiratory syndrome
Acute respiratory distress syndrome (ARDS) is associated with a substantial burden of morbidity and mortality. Prior studies have identified reproducible hyperinflammatory and hypoinflammatory ARDS subphenotypes with distinct clinical outcomes and treatment responses. Although recent transcriptomic ...
ORGANISM(S): Homo sapiens (Human) 
2026-10-02 | PXD079948 | Pride
Lc-msms Subphenotype Serum proteins Ards Biomarker 
ProteomicsComprehensive SWATH-MS-Based Proteomic Analysis of Rat-derived Macrophage Cell Lines Treated with iE-DAP, a NOD1 Agonist
Alveolar macrophages play a pivotal role in maintaining pulmonary homeostasis. While their primary function is the phagocytic clearance of xenobiotic substances, our recent studies have demonstrated that they also possess a mechanism for the active uptake of bacterial-derived peptides through peptid...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-07-04 | PXD066610 | Pride
Lc-msms Ie-dap Nod1 Pept2 Rat macrophage 
ProteomicsDisruption of astrocyte-neuron crosstalk in PSP: Integrated evidence from proteomics and MRS
Progressive supranuclear palsy (PSP) is a tauopathy that presents region-specific patterns of neurodegeneration, affecting cortical and subcortical areas with relative selectivity. Among these, the anterior cingulate cortex (ACC) is of particular interest due to its involvement in executive function...
ORGANISM(S): Homo sapiens (Human) 
2026-05-19 | PXD066064 | Pride
Lc-msms Psp Swath Progressive supranuclear palsy Cingulate cortex 
ProteomicsAn integrated proteome and phospho-proteome approach to study BPA toxicity on placenta.
The environmental exposure of various Endocrine disrupting chemicals (EDCs) like Bisphenol-A (BPA), can affect human health by inducing hormonal imbalance important for physiological homeostasis. Pregnant females are more susceptible for BPA mediated toxicity. BPA can reach maternal circulation by i...
ORGANISM(S): Homo sapiens (Human) 
2026-07-14 | PXD074780 | Pride
Bisphenol-a Placenta Extra-villous trophoblast Zenoswath Ecotoxico-proteomics Phosphoproteome 
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