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ProteomicsComprehensive SWATH-MS-Based Proteomic Analysis of Rat-derived Macrophage Cell Lines Treated with iE-DAP, a NOD1 Agonist
Alveolar macrophages play a pivotal role in maintaining pulmonary homeostasis. While their primary function is the phagocytic clearance of xenobiotic substances, our recent studies have demonstrated that they also possess a mechanism for the active uptake of bacterial-derived peptides through peptid...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-07-04 | PXD066610 | Pride
Lc-msms Ie-dap Nod1 Pept2 Rat macrophage 
UnknownQuercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux.
Not available
S-EPMC11904602 | biostudies-literature
UnknownGinsenoside Rg3 protects against iE-DAP-induced endothelial-to-mesenchymal transition by regulating the miR-139-5p-NF-κB axis.
Not available
S-EPMC7031736 | biostudies-literature
UnknowniE-DAP Induced Inflammatory Response and Tight Junction Disruption in Bovine Mammary Epithelial Cells via NOD1-Dependent NF-κB and MLCK Signaling Pathway.
Not available
S-EPMC10094069 | biostudies-literature
ProteomicsPeptidoglycan metabolite photoaffinity reporters reveal direct binding to intracellular pattern recognition receptors and Arf GTPases
Extensive structure-activity studies of iE-DAP and MDP have demonstrated their selective activation of NOD1- and NOD2-expressing cells, respectively. Nonetheless, the direct binding of iE-DAP and MDP to NOD1 and NOD2, respectively, as well as other proteins in mammalian cells has not been systematic...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD012350 | Pride
Mdp Gel-based proteomics Nod2 Hek293t 
UnknownGenetic Correlates of Synergy Mechanisms of Daptomycin Plus Fosfomycin in Daptomycin-Susceptible and -Resistant Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA).
Not available
S-EPMC12299106 | biostudies-literature
UnknownBacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2.
Not available
S-EPMC2574525 | biostudies-literature
UnknownNOD1/RIP2 Pathway Promotes Glioma Progression Through Microglial M2 Polarization.
Not available
S-EPMC12686968 | biostudies-literature
UnknownStrain-Specific Adaptations of Streptococcus mitis-oralis to Serial In Vitro Passage in Daptomycin (DAP): Genotypic and Phenotypic Characteristics.
Not available
S-EPMC7460094 | biostudies-literature
UnknownActivation of the pattern recognition receptor NOD1 augments colon cancer metastasis.
Not available
S-EPMC7026222 | biostudies-literature
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