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MetabolomicsTime-dependent stability of plasma and liver interstitial fluid metabolites during sample handling in mice

This study assesses the stability of metabolite levels in plasma and liver interstitial fluid (IF) from mice subjected to different handling times prior to extraction. Blood and tissues from female C57BL/6J mice were collected and either processed immediately or held on ice for 5, 10, or 30 minut...

2025-12-30 | MTBLS13164 | MetaboLights
MetabolomicsUntargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes
Metabolome analysis in micro physiological models is a challenge due to the low volume of cell culture medium (CCM). Here, we report a LC-MS-based untargeted metabolomics protocol for the detection of hepatocyte extracellular metabolites from micro-scale samples of CCM. Using a single LC-MS method w...
2021-01-04 | MTBLS1794 | MetaboLights
ProteomicsPhosphoproteome Analysis of Cerebrospinal Fluid Extracellular Vesicles in Primary Central Nervous System Lymphoma
Primary central nervous system lymphoma(PCNSL) is a rare extra-nodal non-Hodgkin’s lymphoma and accounts for 3%-4% of central nervous system tumors. Recent studies have highlighted the importance of cerebrospinal fluid derived extracellular vesicles in PCNSL. Extracellular vesicles(EVs) are nanoscal...
ORGANISM(S): Homo Sapiens (human) 
2023-07-12 | PXD040744 | JPOST Repository
MetabolomicsUntargeted Metabolomics of the enthesis interstitial fluid of wild-type and Nlrp3-/- mice with sham operation and injury post 7 days
In order to investigate the effect of the NLRP3 inflammasome on the regeneration of enthesis, we established an enthesis injury and repair model in wild-type and NLRP3-/- mice. The interstitial fluid of enthesis was extracted, and untargeted metabolomics was conducted to discover differential metabo...
2025-07-08 | MTBLS12150 | MetaboLights
OtherProteomic analysis of cerebrospinal fluid extracellular vesicles: A comprehensive dataset.
Data from ProteomeXchange, PXD ID: PXD000608. File: QE1_120417_OPL0006_16_CSFexosomes_SP_DC_G3.mzml. Published as part of J Proteomics. 2014 Apr 24 . From the Abstract: {{i}} Extracellular vesicles (EVs) are present in human cerebrospinal fluid (CSF), yet little is known about their protein composi...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32310000045 | GPMDB
Resource Reanalysis 
ProteomicsProteomics of cerebrospinal fluid microvesicles
Comprehensive proteomic dataset of cerebrospinal fluid (CSF) microvesicles. The aim of this study is to deeply characterize the protein content of microvesicles (MVs) isolated from human cerebrospinal fluid. MVs were isolated from Two CSF pools and their proteome was studied with high sensitivity ma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-23 | MSV000080277 | MassIVE
TranscriptomicsCharacterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles
Exosomes and microvesicles (i.e., extracellular vesicles; EVs) have been identified within ovarian follicular fluid, and recent evidence suggests that EVs are able to elicit profound effects on ovarian cell function. While existence of miRNA within EVs has been reported, it remains unknown if EV si...
ORGANISM(S): Bos taurus 
2016-02-09 | E-GEOD-74879 | biostudies-arrayexpress
TranscriptomicsExtracellular Vesicles in Luminal Fluid of the Ovine Uterus
Exosomes/microvesicles (hereafter referred to as extracellular vesicles) were isolated from the ULF of day 14 cyclic and pregnant ewes using ExoQuick-TC. Extracellular vesicle RNA was pooled (n=4 per status) and analyzed for small RNAs by sequencing on the Ion Torrent PGM platform and analysis with ...
ORGANISM(S): Ovis aries 
2014-01-11 | E-GEOD-53974 | biostudies-arrayexpress
ProteomicsHS_CSF_microvesicles
Proteomics of cerebrospinal fluid microvesicles
ORGANISM(S): Homo Sapiens (human) 
2014-12-31 | PAe005110 | PeptideAtlas
TranscriptomicsscRNA-seq analysis of cell subpopulations of the bronchoalveolar lavage fluid of healthy dogs
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
2020-06-29 | E-MTAB-9265 | biostudies-arrayexpress
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