Extracellular proteases

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Unknown (1205)
Proteomics (148)
Transcriptomics (102)
Genomics (97)
Metabolomics (7)
Models (4)
Other (4)

Organisms

Homo sapiens (88)
Mus musculus (54)
Rattus norvegicus (10)
Chlamydomonas reinhardtii (4)
Salmo salar (3)
cellular organisms (2)
Burkholderia cenocepacia H111 (2)
Paxillus involutus (2)
Ampelomyces quisqualis (2)
Porphyromonas gingivalis (2)
Ovis aries (2)
Ciona robusta (2)
Drosophila melanogaster (2)
Oncorhynchus mykiss (2)
Bacillus subtilis (1)
Euarchontoglires (1)
Mammalia (1)
Octodon degus (1)
Ictalurus furcatus (1)
Clostridium botulinum (1)
Bacillus cereus ATCC 14579 (1)
Staphylococcus epidermidis (1)
Pseudomonas aeruginosa (1)
Ancylostoma caninum (1)
Aspergillus fumigatus (1)
Aspergillus fumigatus Af293 (1)
Aspergillus nidulans (1)
Candidozyma auris (1)
Equus caballus (1)
Gallus gallus (1)

Organisms

Homo sapiens (21)
Mus musculus (12)
Aspergillus oryzae 3.042 (3)
Aspergillus oryzae 100-8 (3)
Ampelomyces quisqualis (2)
Porphyromonas gingivalis (2)
Ciona robusta (2)
Salmo salar (2)
Rattus norvegicus (2)
Drosophila melanogaster (2)
Tortispora caseinolytica NRRL Y-17796 (1)
Colwellia psychrerythraea (1)
Pseudoalteromonas aliena (1)
Pochonia chlamydosporia 170 (1)
Dichelobacter nodosus (1)
Ostrea edulis (1)
Brevibacterium linens (1)
Aspergillus ochraceus (1)
Aspergillus nidulans (1)
Streptococcus mutans (1)
Aeromonas hydrophila (1)
Bacillus subtilis subsp. subtilis (1)
Chlamydomonas reinhardtii (1)
Bacillus sp. CN2 (1)
Aspergillus fumigatus (1)
Ancylostoma caninum (1)
Aspergillus ustus (1)
Streptococcus thermophilus (1)
Ovis aries (1)
Bacillus velezensis (1)

Repository

pride (117)
ENA (94)
geo (56)
biostudies-arrayexpress (52)
MassIVE (16)
jPOST (9)
MetaboLights (6)
iProX (5)
BioModels (4)
GPMDB (2)
GNPS (1)

Tissue

Cell culture (27)
Fibroblast (6)
Epithelial cell (5)
Kidney (5)
Plant cell (5)
Keratinocyte (4)
Permanent cell line cell (4)
Blood plasma (3)
Brain (3)
Cell suspension culture (3)
Leaf (3)
Neutrophil (3)
Wound fluid (3)
B cell (2)
Extracellular vesicle (2)
Heart (2)
Lung (2)
Macrophage (2)
Skin (2)
Sputum (2)
T cell (2)
Tail (2)
Urine (2)
Aorta (1)
Articular cartilage (1)
Atherosclerotic plaque (1)
Blood (1)
Blood serum (1)
Cardiac muscle cell (1)
Chondrocyte (1)

Disease

Cardiovascular system disease (4)
Disease free (4)
Membranous glomerulonephritis (3)
Not Available (2)
Cystic fibrosis (2)
Malignant neoplasm of ovary (2)
Osteoarthritis (2)
Wounds and Injuries (2)
Acute leukemia (1)
Alport syndrome (1)
Atherosclerosis (1)
Breast cancer (1)
Candidiasis (1)
Celiac disease (1)
Chronic kidney disease (1)
Dilatation of the ascending aorta (1)
Melanoma (1)
Neuroblastoma (1)
Osteomyelitis (1)
Plasmodium malariae malaria (1)
Recessive dystrophic epidermolysis bullosa (1)
Retinal detachment (1)
Synucleinopathy (1)
Ureteral obstruction (1)
Urinary bladder cancer (1)
Weill-Marchesani syndrome (1)

Technology Type

Mass Spectrometry (117)
Shotgun proteomics (65)
Bottom-up proteomics (25)
Data-dependent acquisition (19)
Gel-based experiment (14)
Data-independent acquisition (6)
SWATH MS (6)
Affinity purification coupled with mass spectrometry proteomics (5)
Top-down proteomics (5)
Mass spectrometry (4)
NMR spectroscopy (2)
HDMSE (2)
DiaPASEF (1)
Glycoproteomics (1)
Metaproteomics (1)
Proteogenomics (1)
SRM/MRM (1)

Instrument Platform

Q Exactive (8)
Q Exactive Plus (3)
Illumina NovaSeq X (2)
Instrument (2)
Orbitrap Exploris 480 (2)
Nuclear Magnetic Resonance (NMR) - (2)
ScanArray [PerkinElmer] (1)
Illumina NovaSeq 6000 (1)
7890A GC coupled to a 5975C inert XL MSD, with a 7683 series injector (G2614A) (1)
LTQ Orbitrap Velos (1)
LTQ Orbitrap XL (1)
Orbitrap Eclipse (1)
Orbitrap Fusion Lumos (1)
Q-Exactive (1)
TSQ Vantage (1)
Capillary electrophoresis MS - positive (1)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - HILIC (1)
Liquid Chromatography MS - positive - reverse phase (1)
Orbitrap Fusion (Thermo Fisher Scientific) (1)
Orbitrap Fusion (Thermo Fisher Scientific)_negative (1)

Publication Date

2025 (42)
2026 (27)
2024 (17)
2023 (17)
2016 (15)
2021 (15)
2018 (15)
2020 (14)
2019 (14)
2022 (13)
2015 (11)
2014 (9)
2013 (9)
2012 (8)
2017 (8)
2010 (7)
2005 (5)
2011 (5)
2009 (4)
2008 (4)
2007 (4)
2006 (2)

UNIPROT ID/AC

P00747 (1)
P00749 (1)
P04189 (1)
P13800 (1)

CHEBI ID

CHEBI:16857 (3)
CHEBI:17191 (3)
CHEBI:17295 (3)
CHEBI:15422 (2)
CHEBI:15347 (2)
CHEBI:15354 (2)
CHEBI:15603 (2)
CHEBI:15971 (2)
CHEBI:16236 (2)
CHEBI:16414 (2)
CHEBI:16467 (2)
CHEBI:16643 (2)
CHEBI:16761 (2)
CHEBI:16977 (2)
CHEBI:17115 (2)
CHEBI:17196 (2)
CHEBI:17203 (2)
CHEBI:17754 (2)
CHEBI:18019 (2)
CHEBI:18050 (2)
CHEBI:18132 (2)
CHEBI:18183 (2)
CHEBI:30768 (2)
CHEBI:15344 (1)
CHEBI:15355 (1)
CHEBI:15366 (1)
CHEBI:15428 (1)
CHEBI:155898 (1)
CHEBI:15611 (1)
CHEBI:15688 (1)

Metabolite Name

L-Isoleucine (3)
L-Phenylalanine (3)
L-Threonine (3)
ADP (2)
Choline (2)
Ethanol (2)
Glycerol (2)
L-Alanine (2)
L-Arginine (2)
L-Asparagine (2)
L-Glutamine (2)
L-Histidine (2)
L-Leucine (2)
L-Lysine (2)
L-Methionine (2)
L-Proline (2)
L-Serine (2)
L-Valine (2)
Pyroglutamic acid (2)
(S)-Menthone 8-thioacetate (1)
1-[(5-Amino-5-carboxypentyl)amino]-1-deoxyfructose (1)
2,3-Butanediol (1)
2-Aminobutyrate (1)
2-Hydroxy-3-methylpentanoic acid (1)
2-Methylnicotinamide (1)
2-Oxoglutarate (1)
3-Hydroxyisovaleric acid (1)
3-Methyl-2-oxovalerate (1)
3R-hydroxy-butanoic acid (1)
4-Aminobutyrate (1)

First Public Date

2014 (19)
2026 (10)
2025 (10)
2024 (9)
2019 (7)
2017 (7)
2013 (7)
2023 (5)
2018 (5)
2021 (4)
2022 (3)
2020 (3)
2016 (3)
2015 (2)

Modelling Approach

Ordinary differential equation model (3)

Lab affiliation

Department of Molecular Biosciences, University of South Florida, Tampa, FL, USA Center for Antimicrobial Resistance, University of South Florida, Tampa, FL, USA (4)
Aarhus University Department of Biomedicine DK-8000 Aarhus (3)
University Clinic for Poultry and Fish Medicine, University of Veterinary Medicine, Vienna, Austria (3)
Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany (2)
Burns and Trauma Research,School of Biomedical Sciences, Queensland University of Technology (2)
Cleveland Clinic Lerner Research Institute (2)
Weizmann Institute of Science (2)
BOKU University, Vienna, Austria (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich, Gregor-Mendel-Str. 4, 85354 Freising, Germany (1)
Bio-pharmaceutical Analysis Lab; Department of Pharmaceutical Science; University of Milan; Milan, Italy (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. Department of Pharmacy, National University of Singapore, Singapore 117543, Singapore. (1)
CENTD, Instituto Butantan (1)
Center for Basic Research, Biomedical Research Foundation Academy of Athens, Soranou Efesiou 4, Athens 11527 (1)
Centre for Infection and Immunity, Queen’s University Belfast, Belfast, Northern Ireland, BT9 7BL, UK. (1)
DKFZ German Cancer Research Center (1)
Dep. of Biology, University of Fribourg, Switzerland (1)
Departamento de Procesos y Tecnología, Universidad Autónoma Metropolitana-Cuajimalpa,Ciudad de Mexico, Mexico. (1)
Department Molecular Microbiology John Innes Centre Norwich Research Park Norwich, UK (1)
Department of Biochemical Sciences, School of Biosciences, Faculty of Health and Medical Sciences, Edward Jenner Building, University of Surrey (1)
Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA Arkansas Children's Research Institute, 13 Children's Way, Little Rock, AR 72205, USA (1)
Department of Biochemistry and Molecular and Structural Biology Jozef Stefan Institute Slovenia (1)
Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Ljubljana, Slovenia (1)
Department of Bioengineering Center for Autodigestion Innovation University of California at San Diego La Jolla, California USA (1)
Department of Biology, Washington University in St. Louis (1)
Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Denmark (1)
Department of Biomedical Sciences, University of Copenhagen, Denmark (1)
Department of Biomedical engineering, Lerner Research Institute, Cleveland Clinic (1)
Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA (1)
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (1)
Department of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan 46241, South Korea (1)

IsPrivate

False (4)

Model Flag

Non Kinetic (1)

Classification

fungi (10)
bacteria (4)

Modification

+3amu) (1)
4x(15)N labeled L-arginine (1)
4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (38)
RNA-seq of coding RNA (10)
Unknown experiment type (3)
Comparative genomic hybridization by array (1)

Release Date

2020 (104)
2021 (97)
2022 (90)
2019 (82)
2018 (80)
2023 (76)
2024 (73)
2016 (70)
2025 (67)
2015 (64)
2013 (64)
2017 (60)
2014 (49)
2011 (44)
2012 (39)
2010 (39)
2009 (30)
2008 (29)
2007 (25)
2006 (16)
2005 (16)
2026 (11)
2003 (7)
2002 (6)
2001 (5)
1999 (4)
2004 (3)
2000 (3)
1998 (3)
1978 (1)

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Extracellular Matrix Analysis of Human Varicose Veins

To understand the consequences of venous hypertension, normal and varicose veins were evaluated using proteomics approaches targeting the extracellular matrix.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-17 | MSV000080062 | MassIVE

The secreted proteases Aur, ScpA, SspA and SspB suppress virulence of Staphylococcus aureus USA300 by shaping the extracellular proteome

Surface-located and secreted virulence factors of the Gram-positive bacterial pathogen Staphylococcus aureus are key drivers for infection of the human host. Proteolytic enzymes may contribute to virulence by breaking primary barriers and host immune defenses. Therefore, the objective of our present...

ORGANISM(S): Staphylococcus aureus

2025-04-22 | PXD056653 | Pride

Characterization of Early-Phase Neutrophil Extracellular Traps in Urinary Tract Infections

Neutrophils have an important role in rapid antimicrobial defenses against and resolution of urinary tract infections (UTIs). We show that a mechanism known as neutrophil extracellular trap (NET) formation is a strategy to combat pathogens in the urinary tract. Viscous aggregates that were present i...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-03-31 | MSV000080847 | MassIVE

Membrane-anchored serine proteases as regulators of epithelial function.

Not available

S-EPMC9869603 | biostudies-literature

Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans.

Not available

S-EPMC10541181 | biostudies-literature

Extracellular Pneumococcal Serine Proteases Affect Nasopharyngeal Colonization.

Not available

S-EPMC7917122 | biostudies-literature

PROTEOLYTIC ACTIVITIES OF EXTRACELLULAR VESICLES ATTENUATE A-SYNUCLEIN AGGREGATION AND MODULATE ITS TOXICITY

Extracellular vesicles (EVs) are nano-sized lipid vesicles released from cells into the extracellular milieu. We examined the yet unexplored role(s) of EVs in α-synuclein (α-syn) degradation and recipient-cell homeostasis, and whether EVs can affect the processing of extracellular α-syn species, the...

ORGANISM(S): Mus musculus (Mouse)

2025-10-06 | PXD044320 | Pride

Proteomics A-synuclein Extracellular vesicles Proteases

Plasmid-encoded regulator of extracellular proteases in Bacillus anthracis.

Not available

S-EPMC1082805 | biostudies-literature

Diversity of cultivable protease-producing bacteria and their extracellular proteases associated to scleractinian corals.

Not available

S-EPMC7210813 | biostudies-literature

extracellular vesicles from Lactobacillus salivarius SNK-6

proteomic analysis of extracellular vesicles from Lactobacillus salivarius SNK-6

ORGANISM(S): Lactobacillus Salivarius

2023-07-26 | PXD044089 |

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1567 Results

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