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TranscriptomicsTranscription profiling of dfferentiation of human bone marrow derived hMSC with beta-glycerphosphate, ascorbicacidphosphate and dexamethasone for 21 days;evaluated time points d4, d7, d14 and d21 after induction
Differentiation of bone marrow derived hMSC with beta-glycerphosphate, ascorbicacidphosphate and dexamethasone for 21 days;evaluated time points d4, d7, d14 and d21 after induction; reference d-1 (one day before induction; preconfluent 70-80%)
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-3 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of in vitro / in vivo osteoblast comparison-Comparison of in vivo and in vitro developed human osteoblasts
Comparison of the genetic profile of hBM-MSC differentiated in vitro into osteoblasts with in vivo developed osteoblasts derived from hip bone.
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-4 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of human regulatory T cells and effector T cells cultured at standard 37C temperature and in mild hypothermia (33C).
Regulatory T cells (Tregs) play crucial role in maintenance of peripheral tolerance. Numerous clinical trials confirmed safety and efficacy of Treg treatment of for deleterious immune responses. However, Tregs lose their characteristic phenotype and suppressive potential during expansion ex vivo. In...
ORGANISM(S): Homo sapiens 
2017-10-04 | E-MTAB-5322 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human BM-MSC expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability
hBM-MSC were expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability;µA analysis were performed p2/p5 (n=10)and p5/p10 (n=5) to examine if the genetic background of hBM-MSC is changeing during their high-grade expansion;
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-6 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human BM-MSC expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability
hBM-MSC were expanded from p2 until p10 and monitored by FACS, proliferation kinetics and differentiation ability;µA analysis were performed p2/p5 (n=10)and p5/p10 (n=5) to examine if the genetic background of hBM-MSC is changeing during their high-grade expansion;
ORGANISM(S): Homo sapiens 
2007-06-09 | E-MARS-5 | biostudies-arrayexpress
ProteomicsMultiplexed, scheduled high resolution sMRM-HR acquisition on full scan MS/MS instruments
Advances in software and high resolution, high mass accuracy mass spectrometers have expanded their functionality beyond traditional data dependent acquisition (DDA) methods. Using a single platform, an orthogonal quadrupole time-of flight (QqTOF) mass spectrometer, the TripleTOF 5600, we have inve...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Escherichia Coli (ncbitaxon:562) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2015-03-10 | MSV000079077 | MassIVE
TranscriptomicsTranscription profiling of Arabidopsis wild type Col-0 and hsf407 double knock out plants after heat stress
Effect of heat stress on wildtype COL-0 Arabidopsis and hsf4-7 double knock out plants.
ORGANISM(S): Arabidopsis thaliana 
2008-12-31 | E-MEXP-1725 | biostudies-arrayexpress
TranscriptomicsNicotinamide N-Methyltransferase drives fibroblast activation and skin fibrosis in systemic sclerosis
Systemic sclerosis (SSc) is characterized by progressive skin and organ fibrosis driven by persistently activated fibroblasts, however, the mechanisms of dermal fibroblast (DF) activation remain unclear. Nicotinamide N-methyltransferase (NNMT) has been linked to fibrosis in other diseases, but its r...
ORGANISM(S): Homo sapiens 
2026-10-20 | E-MTAB-17207 | biostudies-arrayexpress
TranscriptomicsNicotinamide N-Methyltransferase drives fibroblast activation and skin fibrosis in systemic sclerosis
Systemic sclerosis (SSc) is characterized by progressive skin and organ fibrosis driven by persistently activated fibroblasts, however, the mechanisms of dermal fibroblast (DF) activation remain unclear. Nicotinamide N-methyltransferase (NNMT) has been linked to fibrosis in other diseases, but its r...
ORGANISM(S): Homo sapiens 
2026-10-20 | E-MTAB-17206 | biostudies-arrayexpress
TranscriptomicsHuman bone and marrow niche formation by mesenchymal progenitors in vivo is predefined by an organotypic epigenetic signature
In this study, we have analyzed DNA methylation characteristics of human mesenchymal stem and progenitor cells (MSPCs) form different tissue sources including bone marrow (BM), white adipose tissue (WAT ), umbilical cord (UC) as well as dermal fibroblasts by using the HumanMethylation450K array. Cel...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-41933 | biostudies-arrayexpress
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