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GenomicsTranscriptomic analysis of Hela Ezrin inhibited cells
Transcriptomic analysis of Hela Ezrin inhibited cells
PRJNA1219222 | ENA
ProteomicsPrenylated PALM2 Promotes the Migration of Esophageal Squamous Cancer Cells through Activating Ezrin
Proteins containing a CAAX motif at the C-terminus can occur prenylation modification and regulate the localization and activity of a series of key regulatory proteins, including RAS superfamily members, heterotrimeric G proteins, nuclear lamina protein, and several protein kinases and phosphatases....
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040969 |
ProteomicsEzrin inhibition overcomes acquired resistance to vemurafenib in BRAFV600E-mutated colon cancer and melanoma cells in vitro
In spite of the advancements in targeted therapy for BRAFV600E-mutated metastatic colorectal cancer (mCRC), the development of resistance to BRAFV600E inhibition limits the response rate and durability of the treatment. Better understanding of the resistance mechanisms to BRAF inhibitors will facili...
ORGANISM(S): Homo sapiens (Human) 
2023-08-29 | PXD042499 | Pride
Ezrin Brafv600e Actin cytoskeleton Nsc305787 Colon cancer Ezrin inhibitor Melanoma Braf inhibitor Vemurafenib 
TranscriptomicsTranscriptomic analysis of Hela Ezrin inhibited cells
Ezrin (EZR), a cell membrane to cytoskeleton linker protein, plays key roles in maintaining cellular homeostasis. Its deregulation at various levels strongly correlates with cancer progression, metastasis and higher patient mortality. However, the precise mechanistic basis for its role remains unkno...
ORGANISM(S): Homo sapiens 
2025-09-30 | GSE288768 | GEO
UnknownEzrin Inhibition Up-regulates Stress Response Gene Expression.
Not available
S-EPMC4933238 | biostudies-literature
UnknownEzrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma.
Not available
S-EPMC6445733 | biostudies-literature
ProteomicsThe protein interaction of PALM2 in HEK 293T
We identify the protein interaction of PALM2 in HEK 293T. we find that PALM2 can promote the malignant behaviors of esophageal squamous cancer cell (ESCC). Focusing on the mechanism inside, we reveal that PALM2 promotes the migration of esophageal squamous cancer cells through activating it interact...
ORGANISM(S): Homo Sapiens 
2023-03-08 | PXD040700 |
UnknownCutting Edge: Ezrin Regulates Inflammation by Limiting B Cell IL-10 Production.
Not available
S-EPMC4707057 | biostudies-literature
UnknownCLIC5A binds to and stabilizes the open and active conformation of ezrin.
Not available
S-EPMC12494564 | biostudies-literature
UnknownLoss of ezrin expression reduced the susceptibility to the glomerular injury in mice.
Not available
S-EPMC5852236 | biostudies-literature
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