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TranscriptomicsVEGFR-1 expressed by malignant melanoma initiating cells is required for tumor growth
Melanoma growth is driven by malignant melanoma initiating cells (MMIC) identified by expression of the ATP-binding cassette (ABC) member, ABCB5. ABCB5+ melanoma subpopulations have been shown to overexpress the vasculogenic differentiation markers CD144 (VE-cadherin) and TIE-1 and are associated...
ORGANISM(S): Homo sapiens 
2011-01-13 | E-GEOD-26569 | biostudies-arrayexpress
TranscriptomicsThe long noncoding RNA HOTAIR has tissue and cell type dependent effects on HOX gene expression and phenotype of cancer cells
HOTAIR was found to be overepressed in a subset of urothelial cancer tissues and cell lines compared to normal controls. Ectopic HOTAIR expression in urothelial cancer cells in vitro demonstrated cell type dependent changes in phenotype. While some cell lines showed increased proloferation activity ...
ORGANISM(S): Homo sapiens 
2015-06-05 | E-GEOD-57672 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Yarrowia lipolytica cells during yeastM-BM-^Vhypha transition mediated by the transcription factor ZNC1
Transcriptional profiling was performed on cells grown in YEPD medium at 28 M-0C to an OD600 nm = 1.8, in case of cells grown in exponential phase; alternatively, cells were growth in 1% N-acetylglucosamine and 50 mM citrate buffer pH6.0 at 28 M-0C for different times points (15, 60 and 180 minutes)...
ORGANISM(S): Yarrowia lipolytica 
2011-08-01 | E-MTAB-517 | biostudies-arrayexpress
TranscriptomicsTranscript analyses of cisplatin and Sky1 effects in Saccharomyces cerevisiae
Sky1 is a Saccharomyces cerevisiae rich serine-arginine (SR) protein-specific kinase and its enzymatic activity is essential in the cytotoxicity caused by cisplatin, although the molecular mechanisms supporting this function are not understood. We present a transcriptome analysis discriminating betw...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-41094 | biostudies-arrayexpress
GenomicsA Unifying Model for Molecular Determinants of the Pre-selection VM-oM-^AM-" Repertoire
Analysis of histone modifications in double negative thymocytes from RAG-/- mice For the ChIP-seq, input and immunoprecipitated DNA was given to The Scripps DNA Array Facility, where it was prepared for massively parallel sequencing on Illumina HiSeq 2000.
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-48817 | biostudies-arrayexpress
UnknownVery-large-scale-integrated high quality factor nanoantenna pixels.
Not available
S-EPMC11835417 | biostudies-literature
UnknownFat-specific protein 27 inhibits lipolysis by facilitating the inhibitory effect of transcription factor Egr1 on transcription of adipose triglyceride lipase.
Not available
S-EPMC4031504 | biostudies-literature
TranscriptomicsDEN-induced HCC in c-Met knockout mice
HGF has been reported to have both positive and negative effects on carcinogenesis. Here we show that the loss of c-Met signaling in hepatocytes enhanced rather than suppressed the early stages of chemical hepatocarcinogenesis. c-Met conditional knockout mice (c-metfl/fl, AlbCre+/-; MetLivKO) treate...
ORGANISM(S): Mus musculus 
2008-08-09 | E-GEOD-8747 | biostudies-arrayexpress
ProteomicsSigB modulates expression of novel SigB regulon members via Bc1009 in non-stressed and heat-stressed cells revealing its alternative roles in Bacillus cereus
Protein samples were measured using the LC-MS/MS platform containing reversed-phase nano liquid chromatography (nano Acquity M-class UPLC) (Waters Corporation, Massachusetts, USA), which was coupled to nanospray ionization tandem mass spectrometry with traveling wave ion mobility using high-definiti...
ORGANISM(S): Bacillus Cereus Atcc 14579 (ncbitaxon:226900) 
MSV000090315 | MassIVE
Unknown1.2 V Differential Difference Transconductance Amplifier and Its Application in Mixed-Mode Universal Filter.
Not available
S-EPMC9101344 | biostudies-literature
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