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Pseudomonas sp. ZH-FAD Genome sequencing and assembly
Adipogenic differentiation and metabolic adaptation are initiated through transcriptional and epigenetic reprogramming. In particular, dynamic changes in histone modifications may play central roles in the rearrangement of gene expression patterns. LSD1 (KDM1) protein, encoded by aof2 gene, is a his...
ORGANISM(S): Mus musculus 
Alzheimer’s disease (AD) is the leading cause of late onset dementia. However, to date, no efficient therapy for AD is available. Here, we identified a neuroprotective role of the liver contributing to brain amyloid-β (Aβ) homeostasis. The hippocampus is a crucial region for learning and memory and ...
ORGANISM(S): Mus musculus (Mouse) 
2023-06-22 | PXD037361 | Pride
Alzheimer’s disease (AD) is the most common neurodegenerative dementia. Around 10% of cases present an age of onset before 65 years-old, which in turn can be divided in monogenic or familial AD (FAD) and sporadic early-onset AD (EOAD). Mutations in PSEN1, PSEN2 and APP genes have been linked with FA...
ORGANISM(S): Homo sapiens 
Bacillus amyloliquefaciens strain:Fad 108 Genome sequencing
We explored the interactome of flavin adenine dinucleotide (FAD) and the matrix of UV-immobilised FAD bound more than 3,000 proteins from SW-620 lysate. GO enrichment analysis showed that about 600 RNA-binding proteins were bound to FAD beads and, surprisingly, more than 40 proteins showed clear dos...
ORGANISM(S): Homo sapiens (Human) 
2022-10-06 | PXD036953 | Pride
Transcriptome analysis using Arabidopsis leaves after exogenous FAD treatment
Identification of FAD subtypes in mouse HCC models
Hepatitis C virus RNA is 5’ flavin adenine dinucleotide (FAD) capped
Neurotransmitters have been well-documented to determine immune cell fates; however, whether and how γ-amino butyric acid (GABA) shapes the function of innate immune cells is still obscure. Here, we demonstrated that GABA orchestrates macrophage maturation and inflammation. GABA treatment during mac...
2023-01-31 | MTBLS6337 | MetaboLights
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