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MetabolomicsRP-based analysis of human faecal samples using the ZenoTOF 7600

This study contains replicated measurements of a reference human fecal sample from BioIVT. It serves as test and training data for metabolite annotation.

2025-08-07 | MTBLS8356 | MetaboLights
MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
ProteomicsInvestigate the proteomic profiles of calf faecal extracellular vesicles: investigating gut health and infectious disease associated changes in calves
Faeces are considered easily accessible biological specimens that can be used to monitor gastrointestinal disorders. Extracellular vesicles (EVs) can be enriched from calf faeces, and these faecal extracellular vesicles (fEVs) consist of a diverse range of biological molecules, such as proteins, DNA...
ORGANISM(S): Bos taurus (Bovine) 
2026-01-23 | PXD068377 | Pride
Gut infections Proteomics Faecal Extracellular vesicles 
ProteomicsQuantitative label-based canine faecal proteomics
In small animals, diarrhoea is a regular presentation, the aetiology of which can be varied, from an isolated self-limiting event to more serious episodes requiring symptomatic and supportive treatment. Chronic diarrhoea, defined as diarrhoea lasting longer than 3 weeks, is a relatively common probl...
ORGANISM(S): Canis lupus 
2022-08-29 | PXD017454 | Pride
Faecal proteomics Dog Chronic diarrhoea Tandem mass tags 
UnknownFaecal proteomics as a novel method to study mammalian behaviour and physiology.
Not available
S-EPMC8360081 | biostudies-literature
ProteomicsFaecal Proteases and Immune Signatures Drive Subtype-Specific Enteric Neuronal Activation in IBS
Background: Luminal proteases have been implicated in epithelial barrier dysfunction and visceral hypersensitivity in irritable bowel syndrome (IBS), yet their impact on the enteric nervous system (ENS), the principal regulator of gastrointestinal function, remains unknown. We investigated whether ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-10 | PXD071836 | Pride
Protease-activated receptors (pars) Irritable bowel syndrome Serine and cysteine protease activity Faecal supernatant proteomics Luminal–neuronal signalling axis 
UnknownFaecal proteomics links neutrophil degranulation with mortality in patients with alcohol-associated hepatitis.
Not available
S-EPMC11631684 | biostudies-literature
ProteomicsMouse caecum vs faeces - Metaproteogenomics Reveals Taxonomic and Functional Changes between Cecal and Fecal Microbiota in Mouse
We compared the microbiota of paired mouse caecal contents and faeces by applying a multi-omic approach, including 16S rDNA sequencing, shotgun metagenomics, and shotgun metaproteomics. The aim of the study was to verify whether faecal samples are a reliable proxy for the mouse colonic luminal micro...
ORGANISM(S): mouse gut metagenome 
2017-03-31 | PXD004911 | Pride
Caecum Mouse Faeces Gut microbiota Metaproteomics 
UnknownProteomics analysis of faecal proteins in the tick Haemaphysalis flava.
Not available
S-EPMC5806362 | biostudies-literature
ProteomicsMuSt multiomics - Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes
Multiomics of faecal samples collected from individuals in families with multiple cases of type 1 diabetes mellitus (T1DM) over 3 or 4 months. Metagenomic and metatranscriptomic sequencing and metaproteomics were carried out, as well as whole human genome sequencing. Phenotypic data is available.
ORGANISM(S): mixed culture metagenome 
2016-08-22 | PXD003791 | Pride
Human microbiome Gastrointestinal Faecal Type 1 diabetes Families 
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