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ProteomicsMouse EL4 Tumor Proteome Comparison via LC-MSMS
The EL4 mouse tumor model is widely utilized within the field of oncology due to its ease of use and excellent response to chemotherapy, with tumors typically experiencing a reduction in mass of 70% following chemotherapy treatment with cyclophosphamide and etoposide for three days. As not much is k...
ORGANISM(S): Mus musculus (Mouse) 
2017-05-19 | PXD005592 | Pride
Chemotherapy Mouse tumor Tumor death El4 lymphoma Proteomics 
ProteomicsMouse Mammary Gland Morphogenic Differences with BAD 3SA Mutant
The identification of genes driving organ development is central to understanding which signaling pathways drive the pathogenesis of various diseases including cancer. This dataset depicts the proteomic changes observed in C57BL/6J mice expressing wild-type or 3SA-phospho mutant versions of the Bcl-...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-29 | PXD014347 | Pride
Breast Mammary morphogenesis Mouse Breast cancer Mammary gland Bad Lc-ms/ms 
ProteomicsN-terminal acetylation for identification of cleavage sites on immunoprecipitated PrP
In-gel N-terminal acetylation of immunoprecipitated prion protein for identification of cleavage sites. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Three replicates from single brains were included in this experiment.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092543 | MassIVE
ProteomicsSubtiligase N-terminomics for identification of cleavage sites in mice brain and immunoprecipitated PrP
Subtiligase-based N-terminomics (Abu N-terminal tagging) of whole mouse brain and immunoprecipitated prion protein. Mouse expressing either WT or mutant (S3) form of PrP were used in this study. Five replicates for single brain experiments and one replicate for combined brains approach are included....
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092542 | MassIVE
ProteomicsMouse Hepatic Lipid Droplet Proteome under Fasting and Re-Feeding
One of the key functions of the mammalian liver is lipid metabolism. During fasting, lipid storage in the liver increases in order to reserve and provide energy for cellular functions. Upon re-feeding, this reserve of lipids is rapidly depleted; this change is visible, as the organelles responsible ...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-25 | PXD005977 | Pride
Lipid droplet proteome Mouse Lipid metabolism Liver lds Lipid droplets Lc-ms/ms 
ProteomicsProteomic changes in mouse brain expressing WT and mutant (S3) alleles of the prion protein
Label-free quantification of proteomic changes in mouse expressing WT, mutant (S3) prion protein, and PrP-KO mouse. Three biological replicates were included per condition. In-gel digestion of the proteins extracted from brain generated 6 fractions per replicate.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-27 | MSV000092545 | MassIVE
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