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ProteomicsAfucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through NK cell mediated killing
A series of monoclonal antibodies (mAbs) against human immune deficiency virus (HIV) were prepared utilizing different variable regions targeting HIV epitopes in combination with glycoengineering to produce mAbs with low Fc fucosylation. This dataset pertains to the Fc N-glycosylation analysis of th...
ORGANISM(S): Homo sapiens (Human) 
2024-07-30 | PXD053363 | Pride
Lc-ms Monoclonal antibodies Hek-293f cells Antibody glycosylation 
ProteomicsIgG Fc Glycosylation of Total and Disease-Specific Autoantibodies in Systemic Sclerosis
This dataset contains IgG Fc glycosylation profiles of total and antigen-specific autoantibodies from systemic sclerosis (SSc) patients and healthy controls (n = 187). Total IgG and anti-centromere protein B (ACA) and anti-topoisomerase I (ATA) IgG were affinity-purified, digested with trypsin, and ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD083619 | Pride
Human Autoantibodies Systemic sclerosis Lc-ms Plasma Igg fc glycosylation 
ProteomicsMiddle-up analysis of polyclonal IgG-Fc
Middle-up strategy for the analysis of the fragment crystallizable (Fc) region of human plasma immunoglobulins G (IgGs). The use of hydrophilic interaction liquid chromatography (HILIC) and capillary electrophoresis (CE) coupled to mass spectrometry (MS) allowed to get a comprenhesive view of the N-...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-08 | MSV000085388 | MassIVE
ProteomicsSite-specific glycosylation mapping of Fc gamma receptor IIIb from neutrophils of individual healthy donors
The uploaded dateset corresponds to MS1 and MS2 spectra obtained for Fc gamma receptor IIIb isolated from neutrophils of individual healthy donors. They represent NA1/NA2, NA2/NA2, NA2/NA2 allotype respectively. Based on the data, the targeted analysis of the N-glycosylation has been performed for t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-05 | MSV000085913 | MassIVE
UnknownPrehospital cardiac arrest resuscitation practices differ around the globe.
Not available
S-EPMC12329125 | biostudies-literature
UnknownInborn errors of type I IFN immunity in patients with life-threatening COVID-19.
Not available
S-EPMC7857407 | biostudies-literature
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