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Transcriptomicsjejunal Peyer’s patch (JPP) gene expression relative to jejunal mesenteric lymph node (j-MLN) gene expression.
Although immune mechanisms have been described for Peyer’s patch function, in discriminating food nutrients and commensal microflora from pathogenic challenge, an understanding of gene expression patterns associated with normal intestinal homeostasis is lacking. The effects of commensal bacterial co...
ORGANISM(S): Sus scrofa 
2004-11-04 | E-GEOD-1913 | biostudies-arrayexpress
TranscriptomicsSingle cell time course of macrophages exposed to Salmonella enterica subsp. typhimurium
We present a detailed single cell time course of the macrophage response to Salmonella infection. By combining phenotypic fluorescent labels with single cell expression analysis we are able to identify gene modules associated with bacterial exposure and bacterial infection. We also identify other ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65528 | biostudies-arrayexpress
TranscriptomicsGenetic perturbations direct the development of distinct brain tumor types from postnatal neural stem/progenitor cells
Primary brain tumors are classified and treated based on their histological features, however the factors which specify these tumor types remain largely unknown. We demonstrate that the over-expression of HRAS (V12) and MYC alone or in combination directs the development of glioma, CNS PNET, and at...
ORGANISM(S): Mus musculus 
2012-03-21 | E-GEOD-28095 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in 23 Cryptococcus gattii isolates
An array analysis of C. gattii (C. bacillosporus), intended to identify loci associated with the hypervirulence of the Vancouver Island Outbreak (VIO). 23 C. gattii isolates, representing both VIO strains and control strains, were grown for 24 hours in mammalian macrophages. RNA was isolated and g...
ORGANISM(S): Cryptococcus bacillisporus 
2010-05-15 | E-GEOD-17052 | biostudies-arrayexpress
UnknownEpigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
Not available
S-EPMC3848248 | biostudies-literature
UnknownIdentification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
Not available
S-EPMC3709460 | biostudies-literature
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