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TranscriptomicsTranscription profiling of human non-malignant fallopian tube epithelium and high grade serous carcinoma.
The purpose of this study was to identify molecular alterations potentially involved in predisposition to adnexal serous carcinoma (SerCa) in the non-malignant fallopian tube epithelium (FTE) of BRCA1/2-mutation carriers, given recent evidence implicating the distal FTE as a common source for SerC...
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-10971 | biostudies-arrayexpress
ProteomicsGlobal Proteomic Profiling in Chronic Iron-Exposed Fallopian Tube Secretory Epithelial Cells
We previously published (Oncogenesis, Rockfield et al., 2019) that chronic iron exposure (with ferric ammonium citrate, FAC) in immortalized fallopian tube secretory epithelial cells resulted in increased growth and migratory propensity. Our focused analyses identified a subset of oncogenic markers,...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD018416 | Pride
Initiation events Ovarian cancer Proteomic profiling Fallopian tube secretory epithelial cells Ferric ammonium citrate 
TranscriptomicsGene expression profiles of 2D- and 3D-cultured fallopian tube secretory epithelial cells
Background. Fallopian tube secretory epithelial cells (FTSECs) have been implicated as a cell-of-origin for high-grade serous epithelial ovarian cancer. However, there are relatively few in vitro models of this tissue type available for use in studies of FTSEC biology and malignant transformation. I...
ORGANISM(S): Homo sapiens 
2013-09-27 | E-GEOD-51220 | biostudies-arrayexpress
GenomicsTranscriptomic analysis of human fallopian tube secretory epithelium
Transcriptomic analysis of human fallopian tube secretory epithelium
PRJNA756545 | ENA
TranscriptomicsComparative transcriptome analysis between immortalized ovarian surface epithelial (iOSE) and immortalized fallopian tube secretory epithelial (iFTE) cells
The transcriptomes of three immortalized ovarian surface epithelial cell lines (iOSE, PMID: 17266044) and primary OSE cells (Innoprot, Derio, Spain) and four immortalized fallopian tube secretory epithelial (iFTE) cell lines (PMID: 21502498, 22936217) were compared. RNA-sequencing was done from rRNA...
ORGANISM(S): Homo sapiens 
2016-12-15 | E-MTAB-5240 | biostudies-arrayexpress
GenomicsComparative transcriptome analysis between immortalized ovarian surface epithelial (iOSE) and immortalized fallopian tube secretory epithelial (iFTE) cells
Comparative transcriptome analysis between immortalized ovarian surface epithelial (iOSE) and immortalized fallopian tube secretory epithelial (iFTE) cells
PRJEB18066 | ENA
ProteomicsMass Spectrometric Analysis of Clomiphene Citrate-induced Changes in the Secretome Profile of PAX8-positive Human Fallopian Tube Secretory Epithelial Cells and Identification of Biomarkers Relevant to Reproduction and Pregnancy
Clomiphene citrate (CC) is commonly used for infertility treatments, particularly in intrauterine insemination (IUI) and in vitro fertilization (IVF) programs. Despite its effectiveness in inducing ovulation, it is reported to have a low pregnancy rate compared to letrozole. Further, risks of ectopi...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD057963 | Pride
Infertility  ovulation induction  ectopic pregnancy  selective estrogen receptor modulator (serm) 
TranscriptomicsTransformation of the Fallopian Tube Secretory Epithelium Leads to High-grade Serous Ovarian Cancer in BRCA/P53/PTEN Models
Our study presents the first genetic models of de novo high-grade serous carcinomas (HGSC) that originate in fallopian tube secretory epithelial cells and recapitulate the key genetic alterations and precursor lesions characteristic of human invasive ovarian cancer. Genomic copy number analysis, us...
ORGANISM(S): Mus musculus 
2013-12-17 | E-GEOD-49827 | biostudies-arrayexpress
GenomicsEarly response of human ovarian and fallopian tube surface epithelial cells to norepinephrine
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine
PRJNA422427 | ENA
UnknownIn vitro three-dimensional modeling of fallopian tube secretory epithelial cells.
Not available
S-EPMC3849984 | biostudies-literature
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