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ProteomicsInteractome analysis of FAM50A via affinity purification coupled to mass spectrometry
FAM50A missense variants are present in Armfield XLID syndrome patients. Zebrafish lacking fam50a display related phenotypes and show dysregulation of the transcriptome, increased spliceosome mRNAs and a preponderance of 3’ alternative splicing events, suggesting a role for Fam50a in the spliceosome...
ORGANISM(S): Homo sapiens (Human) 
2020-05-08 | PXD017642 | Pride
Protein interactions Streptavidin affinity purification Fam50a Nanolc-ms/ms 
GenomicsFAM50A restrains METTL3–METTL14 catalytic activity to regulate m6A deposition and cell proliferation: FAM50A ChIP-seq
FAM50A restrains METTL3–METTL14 catalytic activity to regulate m6A deposition and cell proliferation: FAM50A ChIP-seq
PRJNA1449505 | ENA
GenomicsTranscriptome profiling following acute FAM50A degradation in HepG2 cells
Transcriptome profiling following acute FAM50A degradation in HepG2 cells
PRJNA1514690 | ENA
GenomicsFAM50A Disruption in TOV21G Cells RNAseq
In this project we aimed to assess the transcriptional consequences of disrupting FAM50A in TOV21G cells in vivo. To do this we generated a dox inducible FAM50A gRNA allele such that we could conditionally inactivate FAM50A by feeding mice a diet containing doxycycline. Tumour masses were harvested ...
EGAS00001004156 | EGA
GenomicsMutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy (human)
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy (human)
PRJNA607976 | ENA
GenomicsMutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy (zebrafish)
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy (zebrafish)
PRJNA607984 | ENA
UnknownMutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy.
Not available
S-EPMC7378245 | biostudies-literature
UnknownFAM50A as a novel prognostic marker modulates the proliferation of colorectal cancer cells via CylinA2/CDK2 pathway.
Not available
S-EPMC11856281 | biostudies-literature
TranscriptomicsTranscriptome profiling following acute FAM50A degradation in HepG2 cells
RNA-seq was performed using non-immunoprecipitated matched input RNA libraries generated from FAM50A-dTAG HepG2 cells treated with DMSO or dTAG-13 for 6 h. The dataset includes strand-specific paired-end libraries from two biological replicates per condition and was used to assess transcript abundan...
ORGANISM(S): Homo sapiens 
2026-10-13 | GSE344151 | GEO
GenomicsFAM50A restrains METTL3–METTL14 catalytic activity to regulate m6A deposition and cell proliferation: FAM50A ChIP-seq
Endogenous FAM50A ChIP-seq was performed in HepG2 cells. The dataset includes two biological replicates, matched input controls, normalized signal tracks, and a reproducible pooled peak set.
ORGANISM(S): Homo sapiens 
2026-10-13 | GSE327138 | GEO
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