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Mechanical force is critical for the development and remodeling of bone. Here we report that mechanical force regulates the production of the metabolite asymmetric dimethylarginine (ADMA) via regulating the hydrolytic enzyme dimethylarginine dimethylaminohydrolase 1 (Ddah1) expression in osteobla...

2021-11-23 | MTBLS3725 | MetaboLights
Untargeted LC-MS metabolomics analysis was performed on McKinley canine osteosarcoma cells (Group A) and PEKCC2382 normal canine osteoblast cells (Group B). This study screens characteristic differential metabolites and elucidates distinct metabolic phenotype discrepancies between malignant osteosar...
2026-07-28 | MTBLS14700 | MetaboLights
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