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ProteomicsGenome-scale CRISPRi screen identifies pcnB repression conferring overproduction of free fatty acids in Escherichia coli
In this study, we carried out genome-scale CRISPRi modulation combining fluorescence-activated cell sorting (FACS) and next-generation sequencing (NGS) to identify genetic determinants for FFAs overproduction in Escherichia coli. The pcnBi (AP) strain that repressed the expression of pcnB produced 2...
ORGANISM(S): Escherichia Coli 
2024-05-18 | PXD052390 |
UnknownImpact of positive cognitive emotion regulation and sense of coherence in the relationship between family hardiness and post-traumatic growth in patients with lung cancer: a mediation analysis study in two tertiary hospitals of China.
Not available
S-EPMC12306214 | biostudies-literature
UnknownInvestigating the Immunogenic Cell Death-Dependent Subtypes and Prognostic Signature of Triple-Negative Breast Cancer.
Not available
S-EPMC11003942 | biostudies-literature
ProteomicsGenome-wide targets identification for high-titer production of free fatty acids in Escherichia coli
We employed omics analyses to identify potential targets in multiple cellular processes, enabling systematical discovery of beneficial chromosomal gene targets that can be engineered to optimize free fatty acids (FFAs) production in Escherichia coli.
ORGANISM(S): Escherichia Coli 
2020-06-03 | PXD017890 |
UnknownG-quadruplex inducer/stabilizer pyridostatin targets SUB1 to promote cytotoxicity of a transplatinum complex.
Not available
S-EPMC8989551 | biostudies-literature
ProteomicsMining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome clustered regularly interspaced short palindromic repeats interference library
In this study, a whole-genome CRISPRi library was developed in Y. lipolytica and applied for enforcing the tolerance to furfural and acetic acid. Several novel gene targets were discovered through NGS before and after screening. And to analyze the tolerance mechanism caused by transcriptional repres...
ORGANISM(S): Yarrowia Lipolytica 
2024-03-31 | PXD051116 |
UnknownTrastuzumab deruxtecan in patients from China with previously treated human epidermal growth factor receptor 2-positive locally advanced/metastatic gastric or gastroesophageal junction adenocarcinoma (DESTINY-Gastric06): results from a single-arm, multicenter, phase 2 trial.
Not available
S-EPMC12359162 | biostudies-literature
ProteomicsProteomics analysis of human amniotic epithelial cell-derived extracellular vesicles
Proteomics analysis of human amniotic epithelial cell-derived extracellular vesicles.
ORGANISM(S): Homo Sapiens 
2021-12-07 | PXD030221 |
UnknownExpert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition).
Not available
S-EPMC6376656 | biostudies-literature
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
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