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GenomicsGATA-2 occupancy in Kasumi-3 cell line
GATA-2 is a master regulator of hematopoiesis which controls expression of multiple genes and is implicated in acute myeloid leukemia (AML). However, the molecular mechanism how GATA-2 deregulation causes leukemogenesis is still unclear. In this study, GATA-2 ChIP-squ analysis was conducted in Kasum...
ORGANISM(S): Homo sapiens 
2016-08-05 | E-GEOD-84782 | biostudies-arrayexpress
ProteomicsReduction of ZFX levels decreases histone H4 acetylation and increases the pause ratio at target promoters
The ZFX transcriptional activator binds to CpG island promoters, with a major peak at ~200-250bp downstream from transcription start sites. Because ZFX binds within the transcribed region, we investigated whether it regulates transcriptional elongation. We used GRO-seq to show that loss or reduction...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD044709 | Pride
Elongation Turboid Pol2 pausing Zfx Transcription 
UnknownNew and Interesting Fungi. 6.
Not available
S-EPMC10966675 | biostudies-literature
GenomicsL3MBTL2 protein acts in concert with PcG protein mediated monoubiquitination of H2A to establish a repressive chromatin structure [ChIP-Seq data].
Human MBT domain-containing protein L3MBTL2 was found to be an integral component of a protein complex that we termed Polycomb Repressive Complex 1-like 3 (PRC1L3) given the presence of the PcG proteins RING1, RING2 and PCGF6. L3MBTL2 binds chromatin in a histone modification-independent manner and ...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-28162 | biostudies-arrayexpress
TranscriptomicsGenome-associated RNA Polymerase II includes the dissociable Rpb4/7 subcomplex
Yeast RNA polymerase (Pol) II consists of a ten-subunit core enzyme and the Rpb4/7 subcomplex, which is dispensable for catalytic activity and dissociates in vitro. To investigate whether Rpb4/7 is an integral part of DNA-associated Pol II in vivo, we used chromatin immuno-precipitation coupled to h...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12060 | biostudies-arrayexpress
UnknownPhysical Activity Supporting Connection to Nature, and Helping to Maintain Wellbeing during the Covid-19 Restrictions in England.
Not available
S-EPMC8123673 | biostudies-literature
UnknownNile Blue-based nanosized pH sensors for simultaneous far-red and near-infrared live bioimaging.
Not available
S-EPMC3798108 | biostudies-literature
UnknownStand Diversity Does Not Mitigate Increased Herbivory on Climate-Matched Oaks in an Assisted Migration Experiment.
Not available
S-EPMC11963489 | biostudies-literature
TranscriptomicsL3MBTL2 protein acts in concert with PcG protein mediated monoubiquitination of H2A to establish a repressive chromatin structure [ChIP-chip data].
Human  MBT  domain‐containing  protein  L3MBTL2  was  found  to  be  an  integral  component  of   a  protein  complex  that  we  termed  Polycomb  Repressive  Complex  1‐like  3  (PRC1L3)  given  the  presence   of  the  PcG  proteins  RING1,  RING2  and  PCGF6.  L3MBTL2  binds  chromatin  in  a  h...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-28161 | biostudies-arrayexpress
UnknownPeptide nucleic acid (PNA) clamps reduce amplification of host chloroplast and mitochondria rRNA gene sequences and increase detected diversity in 16S rRNA gene profiling analysis of oak-associated microbiota.
Not available
S-EPMC11773970 | biostudies-literature
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