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TranscriptomicsEffect of mir-210 over-expression on the miRNAome of human umbilical vein endothelial cells
MicroRNAs (miRNAs) are small non-protein-coding RNAs that are incorporated into the RNA-induced silencing complex (RISC) and inhibit gene expression by regulating the stability and/or the translational efficiency of target mRNAs. miR-210 can be considered a master miRNA of hypoxic response and is cu...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-35365 | biostudies-arrayexpress
GenomicsHDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibroadipogenic progenitors in dystrophic muscles
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration M-bM-^@M-^S is a key determinant in the pathogenesi...
ORGANISM(S): Mus musculus 
2014-04-02 | E-GEOD-52062 | biostudies-arrayexpress
TranscriptomicsImplication of Long noncoding RNAs in the endothelial cell response to hypoxia II.
Long noncoding RNAs (lncRNAs) are non-protein coding RNAs regulating gene expression. Although for some lncRNAs a relevant role in hypoxic endothelium has been shown, the regulation and function of lncRNAs is still largely unknown in the vascular physio-pathology. Taking advantage of next-generation...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-76739 | biostudies-arrayexpress
TranscriptomicsmicroRNAs expression profile in Myotonic Dystrophy type-2 (DM2) patients
Myotonic Dystrophy Type-2 (DM2) is an autosomal dominant disease caused by the expansion of a CCTG tetraplet repeat. It is a multisystemic disorder, affecting skeletal muscles, the heart, the eye, the central nervous system and the endocrine system The expression of 365 miRNAs was measured in the mu...
ORGANISM(S): Homo sapiens 
2012-08-27 | E-GEOD-37794 | biostudies-arrayexpress
TranscriptomicsHypoxia-induced miR-210 modulates gene expression in response to acute peripheral ischemia.
Peripheral Artery Disease is caused by the restriction or occlusion of arteries supplying the leg. Better understanding of the molecular mechanisms underpinning tissue response to acute and chronic ischemia is urgently needed to improve therapeutic options. The aim of this study is understanding miR...
ORGANISM(S): Mus musculus 
2015-10-23 | E-GEOD-43340 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of diabetic and non diabetic patients affected by post-ischemic heart failure
Increased morbidity and mortality associated with post-ischemic heart failure (HF) in diabetic patients underscore the need for a better understanding of the underlying molecular events. Indeed, effective HF therapy in diabetic patients requires a complex strategy encompassing the development of imp...
ORGANISM(S): Homo sapiens 
2012-03-21 | E-GEOD-26887 | biostudies-arrayexpress
UnknownROD1 is a seedless target gene of hypoxia-induced miR-210.
Not available
S-EPMC3443109 | biostudies-literature
UnknownDeregulated microRNAs in myotonic dystrophy type 2.
Not available
S-EPMC3387258 | biostudies-literature
UnknownMicrorna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cells.
Not available
S-EPMC2762614 | biostudies-literature
UnknownMicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3.
Not available
S-EPMC3259646 | biostudies-literature
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