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ProteomicsiTRAQ-based Proteomics Reveals Candidate Proteins of Fat Deposition in Chinese Indigenous Sheep with Morphologically Different Tails
Chinese indigenous sheep can be classified into two types according to their tail morphology: fat-rumped and thin-tailed sheep, of which the typical breeds are Altay sheep and Tibetan sheep, respectively. To identify the differentially expressed proteins (DEPs) underlying the phenotypic differences...
ORGANISM(S): Ovis canadensis mexicana 
2022-02-17 | PXD029488 | Pride
Fat deposit Itraq Type of tail Sheep 
TranscriptomicsResveratrol prevents diet-induced arterial degeneration and stiffening in nonhuman primates
Cardiovascular (CV) disease is a leading cause of morbidity and mortality in Western societies. Even after accounting for traditional CV risk factors (e.g. obesity, smoking and hypertension), the inflammation-driven thickening and stiffening of central arteries is a strong predictor of adverse outco...
ORGANISM(S): Macaca mulatta 
2014-07-21 | E-GEOD-45927 | biostudies-arrayexpress
ProteomicsParacrine Signaling in Visceral Fat
Accumulation of visceral (VIS) as opposed to subcutaneous (SUB) fat is a predictor of metabolic disorders, insulin resistance, and cardiovascular disease. This is due in part to the limited capacity of VIS fat to buffer lipids allowing them to deposit in insulin-sensitive tissues, thus impairing ins...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-21 | PXD014672 | Pride
Paracrine signaling Mouse Visceral fat 
TranscriptomicsA global view of the complexity of the porcine transcriptome using a full-sib pair with extreme phenotypes in growth and fat deposit by deep RNA sequencing (mRNA)
Pig is an important animal model for human obesity and diseases. However, the complexity of the porcine transcriptome is not yet fully elucidated. Here we have used massively parallel high-throughput sequencing of cDNA (RNA-Seq) to generate a high-resolution map of the porcine transcriptome and miRN...
ORGANISM(S): Sus scrofa 
2011-01-12 | E-GEOD-26382 | biostudies-arrayexpress
Methylation profilingDNA methylation landscape of fat deposit and fatty acid composition variation in obese and lean pigs
Obese and lean type pig breeds show obvious differences in fat deposit and fatty acid composition. However, the underlying diversities in DNA methylation that related to the phenotypic differentiation have not been clarified. Here, we employed Landrace pigs (a leaner, Western breed) and Rongchang pi...
ORGANISM(S): Sus scrofa 
2016-04-11 | GSE80096 | GEO
TranscriptomicsA global view of the complexity of the porcine transcriptome using a full-sib pair with extreme phenotypes in growth and fat deposit by deep RNA sequencing (small RNA)
Pig is the important animal model for human obesity and diseases. However, the complexity of the porcine transcriptome is not yet fully elucidated. Here we have used massively parallel high-throughput sequencing of cDNA (RNA-seq) to generate a high-resolution map of the porcine miRNA in liver (LI), ...
ORGANISM(S): Sus scrofa 
2010-12-20 | E-GEOD-25923 | biostudies-arrayexpress
Genomics
Key lncRNAs affecting Landrace pig fat deposit based on backfat transcriptome sequencing
PRJNA660160 | ENA
GenomicsA global view of the complexity of the porcine transcriptome using a full-sib pair with extreme phenotypes in growth and fat deposit by deep RNA sequencing (small RNA)
Pig is the important animal model for human obesity and diseases. However, the complexity of the porcine transcriptome is not yet fully elucidated. Here we have used massively parallel high-throughput sequencing of cDNA (RNA-seq) to generate a high-resolution map of the porcine miRNA in liver (LI), ...
ORGANISM(S): Sus scrofa 
2010-12-20 | GSE25923 | GEO
GenomicsSus scrofa
DNA methylation landscape of fat deposit and fatty acid composition variation in obese and lean pigs
PRJNA317908 | ENA
TranscriptomicsA global view of the complexity of the porcine transcriptome using a full-sib pair with extreme phenotypes in growth and fat deposit by deep RNA sequencing (mRNA)
Pig is an important animal model for human obesity and diseases. However, the complexity of the porcine transcriptome is not yet fully elucidated. Here we have used massively parallel high-throughput sequencing of cDNA (RNA-Seq) to generate a high-resolution map of the porcine transcriptome and miRN...
ORGANISM(S): Sus scrofa 
2011-01-12 | GSE26382 | GEO
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