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MetabolomicsMetabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating long-term multisystem disorder with a central and inexplicably persistent fatigue symptom that is unable to be relieved by rest. Energy metabolism and oxidative stress have been recent focal points of ME/CFS research and i...
2015-06-08 | MTBLS161 | MetaboLights
ProteomicsProteomic Analysis of Cerebrospinal Fluids from Chronic Fatigue Syndrome Patients with and without Co-existing Fibromyalgia
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has given rise to the question whether they are distinct central nervous system (CNS) entities or is one an extension of the other. To investigate th...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-09 | MSV000090685 | MassIVE
TranscriptomicsGene expression analysis of cancer-related fatigue in whole blood from breast cancer survivors
Cancer-related fatigue is one of the most frequent complaints among breast cancer survivors, with a major negative impact on general life. However, the etiology behind this syndrome is still unraveled. Gene expression analysis was performed on whole blood samples from breast cancer survivors classif...
ORGANISM(S): Homo sapiens 
2009-07-01 | E-GEOD-14786 | biostudies-arrayexpress
TranscriptomicsGene Expression in Peripheral Blood Leucocytes in Monozygotic Twins Discordant for Chronic Fatigue
Background. Chronic fatiguing illness remains a poorly understood syndrome of unknown pathogenesis. We attempted to identify biomarkers for chronic fatiguing illness using microarrays to query the transcriptome in peripheral blood leukocytes. Methods. Cases were 44 individuals who were clinically ev...
ORGANISM(S): Homo sapiens 
2009-05-12 | E-GEOD-16059 | biostudies-arrayexpress
MetabolomicsMetabolic features of chronic fatigue syndrome
Not available
ORGANISM(S): Homo sapiens 
ST000450 | MetabolomicsWorkbench
TranscriptomicsMolecular signatures of peripheral blood mononuclear cells following chronic IFN-alpha: Relationship of OAS2 with Depression and Fatigue
Interferon (IFN)-alpha causes high rates of depression and fatigue, and is used to investigate the impact of innate immune cytokines on brain and behavior. However, little is known about transcriptional profiles of circulating immune cells during chronic IFN-alpha administration. Accordingly, genome...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-31187 | biostudies-arrayexpress
TranscriptomicsMolecular-genetic correlates of fatigue in cancer patients receiving localized external beam radiation therapy
The etiology behind cancer-related fatigue (CRF) is currently unknown. The physiological mechanisms of CRF are based on limited evidence that genetic factors, energy expenditure, metabolism, aerobic capacity, and the individual's immune response to inflammation are responsible for the experience of ...
ORGANISM(S): Homo sapiens 
2012-12-21 | E-GEOD-30174 | biostudies-arrayexpress
MetabolomicsInsights into myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) phenotypes through comprehensive metabolomics
Not available
ORGANISM(S): Homo sapiens 
ST000800 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells (PMBCs) from male patients with post-viral chronic fatigue (n=8) and male healthy control subjects (n=7) to identify a gene signature for Chronic Fatigue Syndrome
Human genome-wide Affymetrix GeneChip arrays were used to compare the levels of gene expression in the peripheral blood mononuclear cells (PMBCs) of male patients with post-viral chronic fatigue (n=8) and male healthy control subjects (n=7). Patients and healthy subjects differed significantly in th...
ORGANISM(S): Homo sapiens 
2009-01-30 | E-GEOD-14577 | biostudies-arrayexpress
MetabolomicsInsights into myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) phenotypes through comprehensive metabolomics (part IV)
Not available
ORGANISM(S): Homo sapiens 
ST000813 | MetabolomicsWorkbench
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