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Pluripotent stem cells have been shown to have unique nuclear properties, e.g., hyperdynamic chromatin and large, condensed nucleoli. However, the contribution of the latter unique nucleolar character to pluripotency has not been well understood. Here, we show fibrillarin (FBL), a critical methyltra...
ORGANISM(S): Mus musculus 
In order to study the molecular mechanism of FBL in cells, this project constructed the full length of FBL into the SFB (S-Flag-SBP tag) vector, and constructed a stable cell line overexpressing FBL. Affinity chromatography combined with LC-MS/MS technology to screen FBL interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2023-07-26 | PXD034434 | Pride
Lactiplantibacillus plantarum strain:FBL-3a | isolate:FBL-3a | breed:prokaryote | cultivar:Lactobacillus plantarum Genome sequencing and assembly
Trichoderma hamatum strain:FBL Z32 Genome sequencing
Draft genome sequence of Minimedusa polyspora FBL 503 (Agaricomycotina) with a high biotech potential.
Draft genome sequence of Trichoderma hamatum FBL 587: insights into safe biotechnological application.
We measured the impact of knocking down FBL on the proteome of Homo sapiens.
ORGANISM(S): Homo sapiens (Human) 
2025-11-28 | PXD051268 | Pride
dRNA sequencing of Drosophila FBL KD
In order to identify genes affected in our model of PANK defficiency we profiled fly heads of female flies control or expressing fumble RNAi by the use of the tim-gal4 driver Female fly heads of the indicated strains were collected at 2 different circadian timepoints, RNA extracted, labeled and hybr...
ORGANISM(S): Drosophila melanogaster 
CLASH for 15.5K and FBL proteins in HEK293T cells
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