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ProteomicsFasting, FDFT1 expression and colorectal cancer
First, lentivirus-mediated overexpression of FDFT1 and lentivirus-mediated knockdown of FDFT1 were performed in CT26 cells. Then control CT26 cells, FDFT1 overexpressing CT26 cells and FDFT1 knockdown CT26 cells were cultured under normal medium or fasting mimic medium. Fasting mimic medium was done...
ORGANISM(S): Homo sapiens (Human) 
2020-03-19 | PXD012029 | Pride
Fdft1 Fasting Colorectal cancer 
TranscriptomicsExpression data from FDFT1 overexpression lung cancer cell lines.
FDFT1 catalyzes the first reaction in the mevalonate/isoprenoid pathway, we demonstrated that FDFT1 down-regulation by two shRNAs significantly reduced cell migration and invasion in highly invasive lung cancer cell lines in vitro, as well as in lung metastases in vivo. We used microarrays to detail...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-37868 | biostudies-arrayexpress
TranscriptomicsExpression data from FDFT1 overexpression lung cancer cell lines.
FDFT1 catalyzes the first reaction in the mevalonate/isoprenoid pathway, we demonstrated that FDFT1 down-regulation by two shRNAs significantly reduced cell migration and invasion in highly invasive lung cancer cell lines in vitro, as well as in lung metastases in vivo. We used microarrays to detail...
ORGANISM(S): Homo sapiens 
2012-12-31 | GSE37868 | GEO
GenomicsInhibition of SQLE or FDFT1 in RBE cells by shRNA, or RBE cells treated with lycorine hydrochloride
Inhibition of SQLE or FDFT1 in RBE cells by shRNA, or RBE cells treated with lycorine hydrochloride
PRJNA1005187 | ENA
Genomics
Knockdown of FDFT1
PRJNA738852 | ENA
UnknownFDFT1 maintains glioblastoma stem cells through activation of the Akt pathway.
Not available
S-EPMC11662426 | biostudies-literature
UnknownGene-specific somatic epigenetic mosaicism of FDFT1 underlies a non-hereditary localized form of porokeratosis.
Not available
S-EPMC11080608 | biostudies-literature
UnknownTargeting FDFT1 Reduces Cholesterol and Bile Acid Production and Delays Hepatocellular Carcinoma Progression Through the HNF4A/ALDOB/AKT1 Axis.
Not available
S-EPMC11948044 | biostudies-literature
UnknownFasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression.
Not available
S-EPMC7170903 | biostudies-literature
GenomicsHomo sapiens
Expression data from FDFT1 overexpression lung cancer cell lines.
PRJNA164677 | ENA
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