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TranscriptomicsEffect of BMP4 and noggin on gene expression in murine R1 ES cells
To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h. Undifferentiated R1 ES cells were trea...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-20527 | biostudies-arrayexpress
ProteomicspChem_benchmarking_dataset_redoxome
Data sets are used for benchmarking, pChem, a modification-centric, blind-search tool to provide a streamlined pipeline for unbiased assessing of the performance of chemoproteomic probes. Data were produced from the redoxome profiling experiments using oxoform-specific probes as indicated, including...
ORGANISM(S): Homo sapiens (Human) 
2023-02-27 | PXD027764 | Pride
Chemoproteomics Pchem Redoxome 
UnknownPro-survival and anti-inflammatory roles of NF-κB c-Rel in the Parkinson's disease models.
Not available
S-EPMC6994410 | biostudies-literature
UnknownBrain-specific NRSF deficiency aggravates dopaminergic neurodegeneration and impairs neurogenesis in the MPTP mouse model of Parkinson's disease.
Not available
S-EPMC6555471 | biostudies-literature
UnknownPartial depletion and repopulation of microglia have different effects in the acute MPTP mouse model of Parkinson's disease.
Not available
S-EPMC8349650 | biostudies-literature
ProteomicspChem_benchmarking_dataset_QTRP_diff_ratios
Data sets are used for benchmarking, pChem, a modification-centric, blind-search tool to provide a streamlined pipeline for unbiased assessing of the performance of chemoproteomic probes. Data were produced from the IPM-based QTRP (quantitative thiol reactivity profiling) experiments where light and...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD027762 | Pride
Ipm diff_ratios pchem 
ProteomicspChem_benchmarking_dataset_QTRP_diff_instruments
Data sets are used for benchmarking, pChem, a modification-centric, blind-search tool to provide a streamlined pipeline for unbiased assessing of the performance of chemoproteomic probes. The IPM-based QTRP (quantitative thiol reactivity profiling) data sets were recorded on different LC-MS/MS instr...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD027758 | Pride
Instruments pchem 
ProteomicspChem_benchmarking_dataset_lysinome_profiling
Data sets are used for benchmarking, pChem, a modification-centric, blind-search tool to provide a streamlined pipeline for unbiased assessing of the performance of chemoproteomic probes. Data were produced from the IPM-based QTRP (quantitative thiol reactivity profiling) applications in various spe...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD027789 | Pride
Stp nhs lysinome pchem 
ProteomicspChem_benchmarking_dataset_initial_test_negative_data
we will acquire three types of data sets as negative controls from 1) probe-free samples (i.e., regular proteomics sample), 2) probe-labeled samples without isotope-coding, and 3) probe-free samples treated with isotope reagents (i.e., without probe labeling, peptides cannot be isotopically labeled)...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD032376 | Pride
Negative controls 
ProteomicspChem_benchmarking_dataset_initial_test_negative_data_20220318
we will acquire three types of data sets as negative controls from 1) probe-free samples (i.e., regular proteomics sample), 2) probe-labeled samples without isotope-coding, and 3) probe-free samples treated with isotope reagents (i.e., without probe labeling, peptides cannot be isotopically labeled)...
ORGANISM(S): Homo sapiens (Human) 
2022-12-16 | PXD032392 | Pride
Negative controls 
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