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Genome-wide DNA methylation was studied to identify regions with extreme inter-individual variability, half of which show stability within-person, and some of which show covariation with body mass index consistently and are located in or near genes previously implicated in regulating body weight or ...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE18226: Expression data from human iPS cells and fibroblasts GSE18227: DNA methylation data from human iPS cells and fibroblasts Refer to individual Series
ORGANISM(S): Homo sapiens 
DNA methylation is often inversely correlated with gene expression. We used custom Nimblegen microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated genomic DNA from iPS cells and fibrobla...
ORGANISM(S): Homo sapiens 
DNA methylation is often inversely correlated with gene expression. We used expression microarrays to determine the relationship between DNA methylation and gene expression in 6 iPS cell lines and the fibroblasts from which they were derived. We isolated RNA from iPS cells and fibroblasts for which ...
ORGANISM(S): Homo sapiens 
Histone modification H3K9me2 is associated with gene silencing and forming large heterochromatin domains. But the micro-structure within large H3K9me2 domains and their relationship with DNA methylation remains unclear. This dataset was generated to compare with genome-wide DNA methylation data. Gen...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE27134: DNA methylation data from human iPS cells, ES cells, cord blood, and keratinocytes GSE27186: Expression data of human somatic cell types and induced pluripotent stem cells GSE31742: DNA methylation data from human keratinocyte-de...
ORGANISM(S): Homo sapiens 
Higher eukaryotes must adapt a totipotent genome to specialized cell types with a stable but limited repertoire of functions. One potential mechanism for lineage restriction is changes in chromatin, and differentiation-related chromatin changes have been observed for individual genes. We have taken ...
ORGANISM(S): Mus musculus 
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