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TranscriptomicsExpression Data from Memory P14 Tg CD8 T cells after either saline mock-infection, Pichinde Virus Infection (bystander infection) or Pichinde Virus infection with daily treatment with anti-CD122 (clone TM-b1)
Exposure to inflammatory cytokines driven by bystander cytokines can have profound effects on the function of memory CD8 T cells. Here we transferred a 1-5X10^4 of P14 TCR-tg T cells (specific for gp33-41 of LCMV) on day -1 followed by infection with 2X10^5 PFU of LCMV Armstrong ip to generate memor...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-69791 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq of Human T lymphocyte derived from H7N9 infected patients
Comparing transcriptomes of CD8 T cells derived from a fatal H7N9 influenza infection with those derived from a patient that survived the infection. Specifically, CD38+ HLA-DR+ cells were sorted by flow cytometry at different sampling time-points, and the transcriptome was analysed using Smart-seq2.
ORGANISM(S): Homo sapiens 
2018-01-30 | E-MTAB-6379 | biostudies-arrayexpress
TranscriptomicsExpression and functions of long noncoding RNAs during human T helper cell differentiation
To improve our understanding of lncRNA expression in T cells, we used whole genome sequencing (RNA-seq) to identify lncRNAs expressed in human T cells and those selectively expressed in T cells differentiated under TH1, TH2, or TH17 polarizing conditions. The majority of these lineage-specific lncR...
ORGANISM(S): Homo sapiens 
2015-04-23 | E-GEOD-66261 | biostudies-arrayexpress
TranscriptomicsMouse melanoma types with various genotypes
Only a subset of melanoma patients has evidence for spontaneous T cell infiltration into tumor sites, previously associated with clinical responses. However, the molecular mechanisms explaining absence of a T cell response are not yet defined. Analyses of human melanoma metastases have revealed that...
ORGANISM(S): Mus musculus 
2015-02-28 | E-GEOD-63543 | biostudies-arrayexpress
UnknownThe earliest domestic cat on the Silk Road.
Not available
S-EPMC7347622 | biostudies-literature
TranscriptomicsIL-13 Stimulated Esophageal Epithelial miRNA
miRNA profiling of unstimulated and IL-13 stimulated esophageal epithelial cells
ORGANISM(S): Homo sapiens 
2012-06-26 | E-MEXP-3351 | biostudies-arrayexpress
UnknownA functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs.
Not available
S-EPMC4453034 | biostudies-literature
TranscriptomicsTranscription profiling by array of human bronchial epithelial cells stimulated with IL-13
Human bronchial epithelial cells were stimulated without or with 100 ng/mL IL-13 for 24 hours.
ORGANISM(S): Homo sapiens 
2012-07-05 | E-MEXP-3353 | biostudies-arrayexpress
TranscriptomicsIL-13 miR-375 Esophageal Epithelial Cell
Expression profiling of Control transduced and Pre-miR-375 transduced esophageal epithelial cells stimulated with or without IL-13
ORGANISM(S): Homo sapiens 
2012-06-27 | E-MEXP-3345 | biostudies-arrayexpress
TranscriptomicsMyeloid derived suppressor cells enhance stemness of cancer cells by inducing miRNA101 and suppressing the corepressor CtBP2
The work identifies an immune associated cellular, molecular and clinical network involving MDSCs-microRNA101-CtBP2-stem cell core genes, which extrinsically controls cancer stemness and impacts patient outcome. Primary ovarian cancer cells (5 x105) were co-cultured with freshly sorted ovarian cance...
ORGANISM(S): Homo sapiens 
2013-08-23 | E-GEOD-50082 | biostudies-arrayexpress
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