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Transcriptomics3C-seq of HT29 cells with CCAT1-L knockdown or scramble knockdown
CCAT1-L is a highly expressed long noncoding RNA located in the colorectal cancer specific super enhance region about 500 kb upstream of MYC gene. Knockdown of CCAT1-L significantly down-regulated interaction frequency between CCAT1 and MYC locus and repress MYC expression, suggesting a long-range c...
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55261 | biostudies-arrayexpress
TranscriptomicsRNA-seq from paired human CRC/control mucosa samples
We have used RNA-seq to examine gene expression from paired human CRC/control mucosa samples and identified CRC-specific expressed long noncoding RNAs To identify CRC-specific expressed genes, including long noncoding RNAs
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55259 | biostudies-arrayexpress
MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
GenomicsPlants regenerated from tissue culture contain stable epigenome changes in rice
Most transgenic crops are produced through tissue culture. The impact of utilizing such methods on the plant epigenome is poorly understood. Here we generated whole-genome, single-nucleotide resolution maps of DNA methylation in several transgenic rice lines. We found that all tested transgenic plan...
ORGANISM(S): Oryza sativa Japonica Group 
2013-03-26 | E-GEOD-42410 | biostudies-arrayexpress
TranscriptomicsGene expression profiling during storage root formation in sweet potato
A Microarray experiment was carried out in order to establish the genetic processes and control mechanism involved during storage root formation in Sweetpotato. A Sweetpotato cDNA chip was created from five varieties covering all the growth stages between them. mRNA from primordial root, fibrous roo...
ORGANISM(S): Ipomoea batatas 
2008-12-23 | E-GEOD-13809 | biostudies-arrayexpress
UnknownModeling Pregnancy Outcomes through Sequentially Nested Regression Models.
Not available
S-EPMC9454338 | biostudies-literature
UnknownHigher Nitrogen Uptakes Contribute to Growth Advantage of Invasive <i>Solanum rostratum</i> over Two Co-Occurring Natives Under Different Soil Nitrogen Forms and Concentrations.
Not available
S-EPMC11901527 | biostudies-literature
ProteomicsiTRAQ-based proteomic analysis of dentate gyrus in temporal lobe epilepsy with hippocampal sclerosis
Temporal lobe epilepsy (TLE) is the most frequent type of focal epilepsy in adults, typically resistant to pharmacological treatment and mostly present with cognitive impairment and psychiatric comorbidities. The most common neuropathological hallmark in TLE patients is hippocampal sclerosis(HS). Ho...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD023048 | Pride
Temporal lobe epilepsy Dentate gyrus Quantitative proteomics Itraq Hippocampal sclerosis 
TranscriptomicsLong non-coding RNAs and mRNAs expression analysis of HCC
Although many protein-coding genes have been identified to be aberrantly expressed in hepatocellular carcinoma (HCC), the mechanisms that account for development and progression of HCC remain unclear. In recent years, long noncoding RNAs (lncRNAs) have been shown to have critical regulatory roles in...
ORGANISM(S): Homo sapiens 
2011-09-04 | E-GEOD-27462 | biostudies-arrayexpress
GenomicsNext Generation Sequencing analysis of Functional Interactions among Insulator Proteins [Beaf-32 ChIP-seq]
Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how this may impact gene expression remains unclear. Here we identify ‘indirect...
ORGANISM(S): Drosophila melanogaster 
2014-02-01 | E-GEOD-52962 | biostudies-arrayexpress
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