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Cerebral ischemia/reperfusion injury (CI/RI), including neurological behavior deficits, cerebral infarction, blood-brain barrier (BBB) dysfunction, and neuroinflammation, et al. is a severe challenge in treatment of ischemic stroke. Traditional Chinese medicine (TCM) with the characteristics of mult...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-09 | PXD020936 | Pride
Diabetic kidney disease (DKD) has become the leading cause of end-stage renal diseases, but the efficacy of current treatment remains unsatisfactory. The pathogenesis of DKD needs a more in-depth research. Ubiquitin specific proteases 36 (USP36), a member of deubiquitinating enzymes family, has arou...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023347 | Pride
An in vitro mastitis cell model was constructed by treating mammary epithelial cells of dairy goats with LPS and intervening with cyanidin 3-O-galactoside as a way, to elucidate and explore the key mechanisms involved in the process of inflammation alleviation by cyanidin 3-O-galactoside.
ORGANISM(S): Capra hircus (Goat) 
2025-09-15 | PXD063072 | Pride
Giardia lamblia (G. lamblia) disease is a zoonosis with a-infection rate affecting the general population of the world. Despite the constant possibility of damage due to their own metabolism, G. lamblia have survived and evolved to adapt to various environments. However, research on energy-metabolis...
ORGANISM(S): Giardia lamblia P15 
2021-01-04 | PXD022317 | Pride
Protein phosphorylation plays a critical role during the development of malaria parasites. Here, we performed a functional analysis of a Plasmodium berghei Ser/Thr protein phosphatase 6 (PbPP6), which was associated with the plasma membrane of macrogametes and ookinetes. Compared with the wild-type ...
ORGANISM(S): Plasmodium berghei ANKA 
2025-06-27 | PXD053412 | Pride
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