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GenomicsMicroprotein miP-FERMT3 modulates endothelial cell protein catabolism and induces p53-mediated cell cycle arrest and senescence
Microprotein miP-FERMT3 modulates endothelial cell protein catabolism and induces p53-mediated cell cycle arrest and senescence
PRJNA1366365 | ENA
UnknownFERMT3 mediates cigarette smoke-induced epithelial-mesenchymal transition through Wnt/β-catenin signaling.
Not available
S-EPMC8571878 | biostudies-literature
GenomicsCRISPR/Cas9-mediated loss of FERMT3 reveals kindlin-3 independent neutrophil activity in Leukocyte Adhesion Deficiency III.
CRISPR/Cas9-mediated loss of FERMT3 reveals kindlin-3 independent neutrophil activity in Leukocyte Adhesion Deficiency III.
PRJNA1454520 | ENA
UnknownIndependent prognostic biomarker FERMT3 associated with immune infiltration and immunotherapy response in glioma.
Not available
S-EPMC10557566 | biostudies-literature
TranscriptomicsCRISPR/Cas9-mediated loss of FERMT3 reveals kindlin-3 independent neutrophil activity in Leukocyte Adhesion Deficiency III.
Mutations in human FERMT3, which encodes for the kindlin-3 protein, impair integrin activity and function in neutrophils from patients with leukocyte adhesion deficiency III (LAD-III). These patients have severe and recurrent life-threatening bacterial and fungal infections early in life. Although t...
ORGANISM(S): Homo sapiens 
2026-10-02 | GSE328304 | GEO
UnknownA Novel Nonsense Mutation in FERMT3 Causes LAD-III in a Pakistani Family.
Not available
S-EPMC6491447 | biostudies-literature
TranscriptomicsMicroprotein miP-FERMT3 modulates endothelial cell protein catabolism and induces p53-mediated cell cycle arrest and senescence
In this study, the function of a novel 69 amino acid microprotein (miP) encoded by a smORF within the coding sequence of the FERM Domain Containing Kindlin-3 transcript, i.e. miP-FERMT3, was investigated.
ORGANISM(S): Homo sapiens 
2026-07-01 | GSE310464 | GEO
UnknownNovel FERMT3 and PTPRQ Mutations Associated with Leukocyte Adhesion Deficiency-III and Sensorineural Hearing Loss.
Not available
S-EPMC10756723 | biostudies-literature
UnknownImmune-Related Molecules CD3G and FERMT3: Novel Biomarkers Associated with Sepsis.
Not available
S-EPMC10815248 | biostudies-literature
UnknownVariable impairment of platelet functions in patients with severe, genetically linked immune deficiencies.
Not available
S-EPMC5830379 | biostudies-literature
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