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UnknownVIP Promotes Recruitment of Tregs to the Uterine-Placental Interface During the Peri-Implantation Period to Sustain a Tolerogenic Microenvironment.
Not available
S-EPMC6960177 | biostudies-literature
TranscriptomicsAn Ets2-specific transcriptional program in tumor-associated macrophages promotes metastasis
Macrophages have been implicated in breast cancer progression and metastasis, but relatively little is known about the genes and pathways that are involved. Using a conditional allele of Ets2 in the mouse, we have identified Ets2 as a critical gene in tumor associated macrophages (TAMs) that specif...
ORGANISM(S): Mus musculus 
2010-01-05 | E-GEOD-12863 | biostudies-arrayexpress
TranscriptomicsDnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia (Bulk RNA-Seq)
Cytogenetically normal acute myeloid leukemia (CN-AML) represents nearly 50% of human acute myeloid leukemia (AML) cases with a 5-year overall survival of approximately 30%. In CN-AML with poorer prognosis, mutations in the de novo DNA methyltransferase (DNMT3A) and the FMS-like tyrosine kinase 3 (F...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-77846 | biostudies-arrayexpress
TranscriptomicsDnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia (Single Cell RNA-Seq)
Cytogenetically normal acute myeloid leukemia (CN-AML) represents nearly 50% of human acute myeloid leukemia (AML) cases with a 5-year overall survival of approximately 30%. In CN-AML with poorer prognosis, mutations in the de novo DNA methyltransferase (DNMT3A) and the FMS-like tyrosine kinase 3 (F...
ORGANISM(S): Mus musculus 
2016-03-27 | E-GEOD-77847 | biostudies-arrayexpress
TranscriptomicsThe molecular basis of the renal and vascular consequences of Uremia
Background. Chronic renal failure is characterized by progressive renal scarring and accelerated cardiovascular disease. In animal models, this is thought to be due to non-dialyzable uremic toxins M-bM-^@M-^S small, protein-bound molecules normally secreted via Organic Anion Transporters (OATs) in t...
ORGANISM(S): Homo sapiens 
2013-06-30 | E-GEOD-45709 | biostudies-arrayexpress
UnknownInorganic arsenic exposure and neuropsychological development of children of 4-5 years of age living in Spain.
Not available
S-EPMC6541502 | biostudies-literature
UnknownFunctional interplay between c-Myc and Max in B lymphocyte differentiation
Not available
S-SCDT-EMBOR-2018-45770-T | biostudies-other
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
UnknownrmtD2, a new allele of a 16S rRNA methylase gene, has been present in Enterobacteriaceae isolates from Argentina for more than a decade.
Not available
S-EPMC3028771 | biostudies-literature
TranscriptomicsHosts responses in critical disease caused by pandemic H1N1
Critical disease caused by the new 2009 pandemic influenza virus (nvH1N1) is a challenge for physicians and scientist. As evidenced in SARS and H5N1, the development of an effective immune response plays a key role to overcome viral diseases. We studied host`s gene expression signatures, cytokine a...
ORGANISM(S): Homo sapiens 
2011-05-05 | E-GEOD-21802 | biostudies-arrayexpress
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