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TranscriptomicsTranscription profiling of Arabidopsis under hypoxia stress to assess proportion of transcript associated with large polysomes
7d-old WT ler seedlings were submitted to 12h of non-stress (air) or hypoxia-stress treatment under low light conditions (45 uM m-2 s-2), and Total and Large Polysome RNA from both treatments were extracted and hybridized against Affymetrix genome chips. Values were used to evaluate changes in trans...
ORGANISM(S): Arabidopsis thaliana 
2008-06-11 | E-GEOD-2218 | biostudies-arrayexpress
TranscriptomicsRNA-seq of in vitro-generated murine T helper 17 cells
T helper (Th) 17 cells form a T cell subset which is crucial to maintain immunity against extracellular bacteria and fungi at epithelial barriers, but Th17 cells are also enriched at sites of inflammation in autoimmune disease. These sites are commonly characterised by adverse environmental conditio...
ORGANISM(S): Mus musculus 
2017-06-14 | E-MTAB-5692 | biostudies-arrayexpress
UnknownHIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation.
Not available
S-EPMC11063627 | biostudies-literature
ProteomicsDECODING PROTEIN METHYLATION FUNCTION WITH THERMAL STABILITY ANALYSIS
Protein methylation is emerging as an important modification beyond epigenetics. However, systems-wide analyses of protein methylation function lag behind compared to other modifications. Recently, thermal stability analyses have been developed which provide a proxy of a protein functional status. H...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-27 | PXD038939 | Pride
Thermal stability Protein methylation Mouse embryonic stem cells Prmt5 Ezh2 Pisa 
MetabolomicsHif1α-Dependent Uncoupling Of Glycolysis Suppresses Tumor Cell Proliferation
Hypoxia-inducible factor-1α (HIF1α) attenuates mitochondrial activity while promoting glycolysis. Paradoxically, it remains unknown why lower glycolysis is compromised in human clear cell renal cell carcinomas (ccRCC), in which HIF1α acts a tumor suppressor by inhibiting cell autonomous proliferatio...
2024-03-15 | MTBLS8901 | MetaboLights
UnknownLuminescent κ-Carrageenan-Based Electrolytes Containing Neodymium Triflate.
Not available
S-EPMC6471547 | biostudies-literature
TranscriptomicsRNA libraries of sorted CD8+ memory T cells from the spleen and RNA libraries of sorted IELs from the small intestine of C57BL/6J mice
Intraepithelilal lymphocytes (IELs) are located at the intestinal barrier where they can offer swift protection against invading pathogens. However, they are kept in a heightened state of activation resembling effector T cells, but without cytokine production or clonal proliferation. They also posse...
ORGANISM(S): Mus musculus 
2018-07-10 | E-MTAB-6510 | biostudies-arrayexpress
UnknownOutbreak Control and Clinical, Pathological, and Epidemiological Aspects and Molecular Characterization of a Bovine Herpesvirus Type 5 on a Feedlot Farm in Sao Paulo State.
Not available
S-EPMC4454734 | biostudies-literature
UnknownIntegrative perspective of the healthy aging process considering the metabolome, cardiac autonomic modulation and cardiorespiratory fitness evaluated in age groups.
Not available
S-EPMC9734749 | biostudies-literature
TranscriptomicsGenetic characterization of tumor-stage mycosis fungoides
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18098 | biostudies-arrayexpress
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