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ProteomicsLabel-free shotgun proteomics of S. cerevisiae producing starch-like glucans
The synthesis of starch-like glucans can be reconstituted in S. cerevisiae using the genes from Arabidopsis thaliana: heterologous expression of SS1 to SS4, BE2, BE3, ISA1, and ISA2, together with a bacterial ADPglucose pyrophosphorylase gene for substrate provision in yeast strain 29, yielded insol...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-05 | PXD032241 | Pride
Lc-ms/ms Progenesisqi Yeast 
UnknownDissecting a regulatory calcium-binding site of CLC-K kidney chloride channels.
Not available
S-EPMC3514729 | biostudies-literature
TranscriptomicsA large intergenic non-coding RNA induced by p53 mediates global gene repression in the p53 transcriptional response
Recently, more than a thousand large intergenic non-coding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved in mammalian genomes and thus presumably function in diverse biological processes. Here, we report the identification of lincRNAs that are regulated by p53. One of ...
ORGANISM(S): Mus musculus 
2010-08-09 | E-GEOD-21761 | biostudies-arrayexpress
UnknownDifferential voltage-dependent modulation of the ACh-gated K+ current by adenosine and acetylcholine.
Not available
S-EPMC8759768 | biostudies-literature
TranscriptomicsMapping of genome-wide action sites of topoisomerase IIbeta by a functional ChIP-chip technique (eTIP-tiling array)
DNA topoisomerase II (topo II) catalyzes a strand passage reaction in that one duplex is passed through a transient brake in another. Completion of late stages of neuronal development depends on the presence of active isoform (topo IIbeta). We identified topo IIbeta action sites on 7 selected genomi...
ORGANISM(S): Rattus norvegicus 
2010-05-15 | E-GEOD-13145 | biostudies-arrayexpress
TranscriptomicsIdentification of HOXB8 and K LK11 expression levels as potential biomarkers to predict the effects of FOLFOX4 chemotherapy
To measure global gene expression in primary advanced colorectal cancer patients who have undergone fluorouracil, leucovorin and oxaliplatin (FOLFOX4) chemotherapy and screen valuable biomarkers to predict the effects of chemotherapy Samples from primary advanced colorectal cancer patients were col...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-69657 | biostudies-arrayexpress
TranscriptomicsGene expression changes in U937 cells in response to ectopic expression of EVI1 and/or etoposide treatment
Overexpression of ecotropic viral integration site 1 (EVI1) is associated with aggressive disease in acute myeloid leukemia (AML). Despite of its clinical importance, little is known about the mechanism through which EVI1 confers resistance to antileukemic drugs. Here, we show that a human myeloid c...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-GEOD-66660 | biostudies-arrayexpress
UnknownPrognostic relevance of the Golgi mannosidase MAN1A1 in ovarian cancer: impact of N-glycosylation on tumour cell aggregation.
Not available
S-EPMC6889143 | biostudies-literature
UnknownTherapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Not available
S-EPMC6988856 | biostudies-literature
ProteomicsHuman AC16 Cardiac Cells under Doxorubicin Treatment
AC16 acquired from Millipore and cultured in DMEM/F12 with 10% FBS. For the mass spectrometry experiment, the AC16 cells were switched to Fibroblast Growth Medium (FGM-3) with supplements (Promocell) then treated with 0.1 µM doxorubicin for 24 hours, then co-cultured through non-contact transwells w...
ORGANISM(S): Homo Sapiens (human) 
2023-04-22 | PXD041722 | JPOST Repository
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