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ProteomicsProteomics of Arabidopsis seedlings during de-etiolation
Light triggers chloroplast differentiation whereby the etioplast transforms into a photosynthesizing chloroplast and the thylakoid rapidly emerges. However, the sequence of events during chloroplast differentiation remains poorly understood. Here we used whole-seedling proteome data to quantify chan...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-02-16 | PXD021518 | Pride
Arabidopsis thaliana Q exactive hf-x Progenesisqi Chloroplasts De-etiolation 
ProteomicsLabel-free shotgun proteomics of S. cerevisiae producing starch-like glucans
The synthesis of starch-like glucans can be reconstituted in S. cerevisiae using the genes from Arabidopsis thaliana: heterologous expression of SS1 to SS4, BE2, BE3, ISA1, and ISA2, together with a bacterial ADPglucose pyrophosphorylase gene for substrate provision in yeast strain 29, yielded insol...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-05 | PXD032241 | Pride
Lc-ms/ms Progenesisqi Yeast 
MetabolomicsAkkermansia muciniphila attenuates obsessive-compulsive disorder-like behavior by producing L-tyrosine

Obsessive-compulsive disorder (OCD) ranks among the most prevalent psychiatric disorders globally. The impact of the gut microbiota and associated metabolites on OCD remains unclear. Here, we report a remarkable reduction of Akkermansia muciniphila (A. muciniphila) abundance in both patients and ...

2026-08-20 | MTBLS10145 | MetaboLights
MetabolomicsAkkermansia muciniphila attenuates obsessive-compulsive disorder-like behavior by producing L-tyrosine
Obsessive-compulsive disorder (OCD) ranks among the most prevalent psychiatric disorders globally. The impact of the gut microbiota and associated metabolites on OCD remains unclear. Here, we report a remarkable reduction of Akkermansia muciniphila (A. muciniphila) abundance in both patients and mic...
2026-08-20 | MTBLS10141 | MetaboLights
MetabolomicsMechanisms of action of bile acids in pediatric gastroesophageal reflux: Exploration through non-targeted and targeted metabolomics methods

Purpose: To investigate the pathogenesis of pediatric bile reflux gastritis (BRG) using non-targeted and targeted metabolomics analyses of the changes and content differences of bile acids (BAs) in gastric juice. Methods: Data from 25 pediatric BRG patients treat...

2025-12-05 | MTBLS13459 | MetaboLights
ProteomicsPalaeoproteomic profiles of Iron Age teeth from Northwest Thailand
Human skeletal tissue contains an abundance of proteins some of which may be preserved over geological timescales. The profiling of proteins from ancient individuals — or palaeoproteomics —has begun to provide new information about the diseases suffered in past societies. We describe here the first ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-20 | PXD008479 | Pride
Human Teeth Paleoproteome 
ProteomicsViperin; regulating chondrogenic differentiation via CXCL10 protein secretion
Mutations in the RMRP gene are the origin of cartilage-hair hypoplasia. Cartilage-hair hypoplasia is associated with severe dwarfism caused by impaired skeletal development. However, it is not clear why mutations in the RMRP gene lead to skeletal dysplasia. Viperin is a known substrate of RMRP. Sinc...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-15 | PXD006999 | Pride
Mouse Viperin Chondrogenic differentiation 
ProteomicsProteomic comparison of tissue engineered tendon constructs derived young and old cells
Tendon injuries can occur due to sports related incidents, as a result of trauma to overuse or during disease or ageing. Tissue engineering can offer great potential in the treatment of a tendon injury. The preferred cell source is autologous in order to reduce immune response in the treated individ...
ORGANISM(S): Equus caballus (Horse) 
2018-10-26 | PXD005322 | Pride
Tendon Tissue engineered constructs Young and old Lc-ms/ms 
UnknownGingival Exudatome Dynamics Implicate Inhibition of the Alternative Complement Pathway in the Protective Action of the C3 Inhibitor Cp40 in Nonhuman Primate Periodontitis.
Not available
S-EPMC6128774 | biostudies-literature
ProteomicsPRODIGE, Digestomic data of proteolysis after tanin supplementation in the rumen
The main objective of this study was to investigate the effect of tannins on the fate of dietary protein throughout the ruminant digestive tract using a dynamic in vitro digester under controlled conditions
ORGANISM(S): Medicago sativa subsp. x varia 
2022-06-14 | PXD032973 | Pride
Digestomic rumen Label free quantitation Digi Mass spectrometry Proteomic data Peptidomic data 
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