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Human intervention study with two doses of iron (as ferrous gluconate via intestinal perfusion) to study the effect on genome-wide gene expression in the small intestine, in order to obtain detailed information about intestinal transcriptomics in vivo.
ORGANISM(S): Homo sapiens 
Abstract: The crenarchaeal order Sulfolobales collectively contains at least five major terminal oxidase complexes. Based on genome sequence information, all five complexes are found only in Metallosphaera sedula and Sulfolobus tokodaii, the two sequenced Sulfolobales capable of iron oxidization. Wh...
ORGANISM(S): Metallosphaera sedula 

Clostridioides difficile (C. difficile) causes antibiotic-associated diarrhea. Susceptibility to C. difficile infection (CDI) is largely affected by the gut microbiota, which in turn is influenced by diet. However, the mechanism underlying the interplay between diet and the gut mic...

2024-11-12 | MTBLS11336 | MetaboLights
Background: Host iron deficiency is protective against severe malaria as the human malaria parasite Plasmodium falciparum depends on free iron from its host to proliferate. Due to the absence of transferrin, ferritin, ferroportin, and a functional heme oxygenase, the parasite’s essential pathways of...
ORGANISM(S): Plasmodium falciparum 
Bordetella bronchiseptica RB50 was shifted from iron replete to either iron depleted or iron replete media, and samples were taken post shift for transcriptional profiling
ORGANISM(S): Bordetella bronchiseptica 
Transcriptional profile of whole roots of wild-type and pye-1 mutants exposed to 24 hours -Fe were generated Global population increases and climate change underscore the need for better comprehension of how plants acquire and process nutrients such as iron. A systems biology approach was taken to e...
ORGANISM(S): Arabidopsis thaliana 
B. pertussis Tohama I was grown in iron-depleted or iron-replete media and sampled at several time points to assess global gene expression
ORGANISM(S): Bordetella pertussis 
(from abstract): Iron oxidation is a desirable trait of biomining microorganisms, although the mechanism is not well-understood in extreme thermoacidophiles. The complete genome sequence of the extremely thermoacidophilic archaeon Metallosphaera sedula DSM 5348 (2.2 Mb, ~2300 ORFs) provides insights...
ORGANISM(S): Metallosphaera sedula 
B. bronchiseptica RB50 was grown in medium either lacking or containing iron (ferrous sulfate). At various time points, samples were taken for gene expression analysis.
ORGANISM(S): Bordetella bronchiseptica 
Effects of iron starvation on the transcriptional profile of Bacillus anthracis
ORGANISM(S): Bacillus anthracis 
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