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ProteomicsPAD2-mediated citrullination of Fibulin-5 promotes elastogenesis
The formation of elastic fibers is active only in the perinatal period. How elastogenesis is developmentally regulated is not fully understood. Citrullination is a unique form of post-translational modification catalyzed by peptidylarginine deiminases (PADIPADs), including PADIPAD1-4. Its physiologi...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-22 | PXD026238 | Pride
Deiminase Elastic fiber Citrullination Deimination Lung compliance Fibulin-5 
UnknownFibulin-4 and fibulin-5 in elastogenesis and beyond: Insights from mouse and human studies.
Not available
S-EPMC4156930 | biostudies-literature
TranscriptomicsFibulin-5, an integrin-binging matricellular protein, maintains epidermal stem cell heterogeneity during skin aging
The extracellular matrix (ECM) plays a crucial role in building the extracellular environment and translating extracellular information into biochemical signals that sustain organ functions. Fibulin-5 is a multifunctional ECM protein essential for the formation of elastic fibers and the regulation o...
ORGANISM(S): Mus musculus 
2025-05-01 | GSE295189 | GEO
UnknownCompromised Cardiopulmonary Function in Fibulin-5 Deficient Mice.
Not available
S-EPMC8990734 | biostudies-literature
UnknownFibulin-4 and -5, but not Fibulin-2, are Associated with Tropoelastin Deposition in Elastin-Producing Cell Culture.
Not available
S-EPMC3015050 | biostudies-literature
UnknownFibulin-5 inhibits Wnt/β-catenin signaling in lung cancer.
Not available
S-EPMC4558133 | biostudies-literature
UnknownDifferential regulation of elastic fiber formation by fibulin-4 and -5.
Not available
S-EPMC2782046 | biostudies-literature
UnknownFibulin-5 contributes to microfibril assembly in human periodontal ligament cells.
Not available
S-EPMC2775106 | biostudies-literature
UnknownFibulin-5 deficiency causes developmental defect of premaxillary bone in mice.
Not available
S-EPMC4628642 | biostudies-literature
UnknownFibulin-5 suppresses lung cancer invasion by inhibiting matrix metalloproteinase-7 expression.
Not available
S-EPMC2719681 | biostudies-literature
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