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TranscriptomicsRegulation of filamentation in the human fungal pathogen Candida tropicalis
The yeast-filament transition is essential for the virulence of a variety of fungi that are pathogenic to humans. N-acetylglucosamine (GlcNAc), a ubiquitous molecule in both the environment and host, is one of the most potent inducers of filamentation in Candida albicans and thermally dimorphic fung...
ORGANISM(S): Candida tropicalis MYA-3404 
2016-07-01 | E-GEOD-73340 | biostudies-arrayexpress
ProteomicsOnline Microfluidics Mass Spectrometry Reveals Molecular Responses of Bacterial Filamentation and Inhibition Methods of Drug Resistant Bacteria
Filamentation is one of the self-saving responses and a survival strategy of bacteria in the circumstance of antibiotics. Understanding the molecular mechanism of filamentation can lead to the development of new inhibition methods for antibiotic-resistant bacteria. In this work, we develop an online...
ORGANISM(S): Escherichia Coli 
2021-02-26 | PXD024394 |
TranscriptomicsMicroevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant
Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of drug resistance. Here we used an experimental...
ORGANISM(S): Candida albicans 
2015-03-31 | E-GEOD-56174 | biostudies-arrayexpress
GenomicsFunctional divergence of a global regulatory complex governing fungal filamentation
Functional divergence of a global regulatory complex governing fungal filamentation
PRJNA482366 | ENA
ProteomicsThe adaptive metabolic response involves specific protein glutathionylation during the filamentation process in the pathogen Candida albicans
Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to the systemic disease candidiasis. Its ability to adopt various morphological forms, such as unicellular yeasts, filamentous pseudohyphae and hyphae, contributes to its ability to s...
ORGANISM(S): Candida albicans (Yeast) 
2016-04-21 | PXD003685 | Pride
Candida albicans / filamentation/ glutathionylation/ isocitrate lyase / mitochondria 
ProteomicsC. albicans cells exhibit specific proteomic profiles depending on the medium used to induce the filamentation process
Candida albicans is an opportunist pathogen responsible for a large spectrum of infections, from superficial mycosis to systemic diseases known as candidiasis. C. albicans can grow in various morphological forms, including unicellular budding yeasts, filamentous pseudophyphae and true hyphae, and th...
ORGANISM(S): Candida albicans (Yeast) 
2024-10-31 | PXD052475 | Pride
Candida albicans Metabolism Oxidative stress Proteomic Filamentation 
TranscriptomicsFilamentation involves two overlapping, but distinct, programs of filamentation in the pathogenic fungus Candida albicans
The ability of the human pathogenic fungus Candida albicans to switch between yeast-like and filamentous forms of growth has long been linked to pathogenesis. Numerous environmental conditions, including growth at high temperatures, nutrient limitation, and exposure to serum, can trigger this morpho...
ORGANISM(S): Candida albicans 
2017-09-28 | GSE99902 | GEO
TranscriptomicsRegulation of filamentation in the human fungal pathogen Candida tropicalis
The yeast-filament transition is essential for the virulence of a variety of fungi that are pathogenic to humans. N-acetylglucosamine (GlcNAc), a ubiquitous molecule in both the environment and host, is one of the most potent inducers of filamentation in Candida albicans and thermally dimorphic fung...
ORGANISM(S): Candida tropicalis MYA-3404 
2016-07-01 | GSE73340 | GEO
UnknownFilamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans.
Not available
S-EPMC5677161 | biostudies-literature
GenomicsThe zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans
The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans
PRJNA601775 | ENA
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