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TranscriptomicsGene expression profiling of liver biopsies from 21 chronic hepatitis C patients undergoing antiviral therapy
This dataset is part of the paper: Pegylated interferon-α regulates hepatic gene expression by transient activation of the Jak-STAT pathway; Dill MT et al; Journal of Clinical Investigation; in review Pegylated interferon-α (pegIFN-α) has replaced un-modified recombinant IFN-α for the treatment of c...
ORGANISM(S): Homo sapiens 
2014-01-30 | E-GEOD-48445 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of 6 acute hepatitis C patients
Approximately 50% of patients with chronic hepatitis C (CHC) have a sustained virologic response (SVR) to treatment with pegylated interferon (pegINF)-M-NM-1 and ribavirin. Non-response to treatment is associated with constitutively increased expression of IFN-stimulated genes (ISGs) in the liver. T...
ORGANISM(S): Homo sapiens 
2012-06-08 | E-GEOD-38597 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of primary human hepatocytes treated with IFN-alpha or IFN-gamma
Approximately 50% of patients with chronic hepatitis C (CHC) have a sustained virologic response (SVR) to treatment with pegylated interferon (pegINF)-α and ribavirin. Non-response to treatment is associated with constitutively increased expression of IFN-stimulated genes (ISGs) in the liver. Treatm...
ORGANISM(S): Homo sapiens 
2012-06-08 | E-GEOD-38147 | biostudies-arrayexpress
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