Sort   by:  
 Page size 
TranscriptomicsThe impact of RNAi on the Saccharomyces castellii transcriptome
RNAi, a gene-silencing pathway triggered by double-stranded RNA, is conserved in diverse eukaryotic species but has been lost in the model budding yeast, Saccharomyces cerevisiae. We report that RNAi is present in other budding-yeast species, including Saccharomyces castellii and Candida albicans. ...
ORGANISM(S): Naumovozyma castellii 
2009-09-10 | E-GEOD-17870 | biostudies-arrayexpress
TranscriptomicsSALL4 ChIP-chip using NimbleGen HG18 RefSeq Promoter tiling array (2.7kb)
Increasing studies suggest that SALL4 may play vital roles in leukemogenesis. We have used chromatin immunoprecipitation followed by microarray hybridization as a screening tool to determine potential genes that may account for the role SALL4 plays in leukemogenesis. Analysis of SALL4 binding sites ...
ORGANISM(S): Homo sapiens 
2008-05-17 | E-GEOD-10734 | biostudies-arrayexpress
TranscriptomicsSall4 ChIP-chip in mouse ES cell line W4 using NimbleGen MM8 RefSeq Promoter array (2.5kb)
Embryonic stem cells have potential utility in regenerative medicine due to their pluripotent characteristics. Sall4, a zinc-finger transcription factor, is expressed very early in embryonic development with Oct4 and Nanog, two well characterized pluripotency regulators. Sall4 plays an important rol...
ORGANISM(S): Mus musculus 
2008-09-01 | E-GEOD-11305 | biostudies-arrayexpress
TranscriptomicsTranscription profiling, Rpd3 ChIP-chip and histone H4 and TATA binding protein ChIP-chip of wild type, cti6 and sfl1 yeast mutants
Effects of genetic modification of trans-acting transcription factors and a chromatin remodeler on noncoding RNA transcription and trans-acting factor binding at loci in yeast.
ORGANISM(S): Saccharomyces cerevisiae 
2010-03-29 | E-MEXP-2269 | biostudies-arrayexpress
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
ProteomicsLongitudinal Analysis of the Lung Proteome Reveals Persistent Repair Months after Mild to Moderate COVID-19
In order to assess the restoration of homeostasis in the lung proteome after COVID-19 infection, we performed bronchoalveolar lavage on 45 patients with mild to moderate disease at three phases (acute, recovery, convalescence) over a year. Changes in proteins were assessed using a multimodal approac...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-30 | MSV000094898 | MassIVE
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
TranscriptomicsGenome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma (PDAC)
Determine methylation pattern in PDAC a genome-wide analysis was performed in a cohort of 167 PDAC and 29 adjacent pancreatic tissues samples using the Infinium 450k methylation arrays (Illumina). 167 pancreatic tumors (PDAC) x 29 adjacent -non tumor samples.
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-49149 | biostudies-arrayexpress
UnknownThe National Lung Screening Trial: overview and study design.
Not available
S-EPMC3009383 | biostudies-literature
UnknownFirst results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma.
Not available
S-EPMC5975654 | biostudies-literature
Sort   by:  
 Page size