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ProteomicsOvarian high grade serous carcinoma ascites cell secretome
The secretomes of tumor cells, and macrophages from high grade serous ovarian carcinoma from the ascites of patients undergoing primary surgery were analysed after 24h culture (ex vivo) via obitrap.
ORGANISM(S): Homo sapiens (Human) 
2017-11-17 | PXD008047 | Pride
Macrophages Cancer Hgsoc Ovca Secretome 
ProteomicsOvarian high grade serous carcinoma ascites cell proteoms
Tumor cells, macrophages and T cells from high grade serous ovarian carcinoma from the ascites of patients undergoing primary surgery were analysed without culturing (ex vivo) via obitrap.
ORGANISM(S): Homo sapiens (Human) 
2017-11-17 | PXD006138 | Pride
Ovca Cancer High grade serous ovarian carcinoma Human Macrophages Hgsoc T cells Ovarian carcinoma 
GenomicsSP1/2/3 and NfY cooccurency in MEFs
Investigation of the binding behaviour of Sp1, Sp2, Sp3 and NF-ya, NF-yb and NF-yc in mouse embryonic fibroblasts and of Sp1, Sp2 and Sp3 in HEK-293 cells reveals distinct binding of the seemingly similar transcription factors Sp1/3 and Sp2.
ORGANISM(S): Mus musculus 
2015-01-30 | E-MTAB-2970 | biostudies-arrayexpress
TranscriptomicsGenome-wide Analysis of Sp2 Occupancy and Expression Profiling Establish Sp2 as a Sequence-specific Transcription Factor Regulating Fundamental Cellular Processes - Expression Profiling
Mouse embyronic fibroblasts (MEFs) were depleted for transcription factor Specificity Factor 2 (Sp2) via Cre-Recombinase, harvested either 7 days or several weeks post infection and their expression profile compared to mock-infected MEFs.
ORGANISM(S): Mus musculus 
2012-05-24 | E-MTAB-1015 | biostudies-arrayexpress
TranscriptomicsRNAi profiling by array of human WPMY-1 cells with PPARbeta/delta knock down and exposure to PPAR agaonists
Human WPMY-1 cells were depleted for PPARbeta/delta and exposed to the PPAR agonists GW501516.
ORGANISM(S): Homo sapiens 
2010-12-31 | E-MEXP-2756 | biostudies-arrayexpress
TranscriptomicsExpression profiling, Lin-9 depletion array in D3 mES cells
Lin-9 was depleted in ES-D3 cells (ATCC CRL-1934) and the resulting expression profile changes mapped via microarrays
ORGANISM(S): Mus musculus 
2013-05-13 | E-MTAB-1490 | biostudies-arrayexpress
TranscriptomicsNatural Killer cells treated with arachidonic acid, IL-2 and ascites
Natural killer cells were exptracted from PMBCs of healthy donors, exposed to arachidonic acid, Il-2, both, or ascites and their expression changes identified via RNAseq (QuantSeq).
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13971 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human WPMY-1 cells treated with GW501516 ((a PPARbetadelta agonist) or TFGBeta2
Microarray analyses of WPMY-1

cells, either untreated (solvent) or treated with

GW501516 (0.3 µM), TGFBeta2 (10 ng/ml), or

both ligands for 6 h.
ORGANISM(S): Homo sapiens 
2010-07-21 | E-MEXP-2748 | biostudies-arrayexpress
GenomicsGenome-wide analyses define different classes of PPARbetadelta target genes characterized by distinct modes of transcriptional regulation (Sequencing)
Genome-wide occupancy of PPARbeta/delta in human myofibroblast (WPMY-1 celline) was studied with ChIP-Seq. Additionally, H3K4 trimethylation and RNA polymerase II status was examined.
ORGANISM(S): Homo sapiens 
2010-12-31 | E-MTAB-371 | biostudies-arrayexpress
TranscriptomicsThe transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization
RNAseq of peritoneal macrophages from patients with non-malignent peritoneal afflictions.
ORGANISM(S): Homo sapiens 
2016-09-27 | E-MTAB-4764 | biostudies-arrayexpress
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