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MetabolomicsCreation and Characterization of a Genomically Hybrid Strain in the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti
Many bacteria, often associated with eukaryotic hosts and of relevance for biotechnological applications, harbor a multipartite genome composed of more than one replicon. Biotechnologically relevant phenotypes are often encoded by genes residing on the secondary replicons. A synthetic biology approa...
2021-03-17 | MTBLS576 | MetaboLights
MetabolomicsEvidence of a DHA signature in the lipidome and metabolome of human hepatocytes
Cell supplementation with bioactive molecules often causes a perturbation in the whole intracellular environment. Omics techniques can be applied for the assessment of this perturbation. In this study, the overall effect of docosahexaenoic acid (DHA) supplementation on cultured human hepatocyte lipi...
2017-03-02 | MTBLS419 | MetaboLights
MetabolomicsSerum metabolomic profiles identify ER-positive early breast cancer patients at increased risk of disease recurrence in a multicentre population

PURPOSE: Detecting signals of micrometastatic disease in early breast cancer (EBC) patients could improve risk stratification and allow better tailoring of adjuvant therapies. We have previously shown that postoperative serum metabolomic profiles are predictive of relapse in a si...

2017-03-02 | MTBLS424 | MetaboLights
TranscriptomicsFiorentino 2006-7 dermatomyositis, lupus, control skin
Background: Dermatomyositis (DM) is an autoimmune disease that mainly affects the skin, muscle, and lung. The pathogenesis of skin inflammation in DM is not well understood. Methodology and Findings: We analyzed genome-wide expression data in DM skin and compared them to those from healthy controls....
ORGANISM(S): Homo sapiens 
2012-01-12 | E-GEOD-32245 | biostudies-arrayexpress
UnknownRecovering Cucurbita pepo cv. 'Lungo Fiorentino' Wastes: UHPLC-HRMS/MS Metabolic Profile, the Basis for Establishing Their Nutra- and Cosmeceutical Valorisation.
Not available
S-EPMC6514934 | biostudies-literature
ProteomicsNative Mass Spectrometry of Soluble Proteins with Sodium Chloride enabled by a Dendritic Detergent
Salts are pivotal for ligand binding but hamper the analysis of proteins through native mass spectrometry due to adduct formation and consequent signal suppression. Here, we show how to facilitate native mass spectrometry of soluble proteins and protein–ligand complexes in the presence of sodium chl...
ORGANISM(S): Bos taurus (Bovine) Oryctolagus cuniculus (Rabbit) Pseudomonas aeruginosa PAO1 Saccharomyces cerevisiae (Baker's yeast) Equus caballus (Horse) 
2026-09-14 | PXD074233 | Pride
ProteomicsStructural snapshots of Pseudomonas aeruginosa LptB2FG and LptB2FGC reveal insights into lipopolysaccharide recognition and transport - native mass spectrometry data
Gram-negative bacteria are intrinsically resistant to many antibiotics because of densely packed lipopolysaccharides (LPS) in the outer leaflet of their outer membrane (OM), which acts as a highly effective barrier towards the spontaneous permeation of toxic molecules, including antibiotics. LPS are...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-10-22 | PXD069660 | Pride
Lipopolysaccharide Lps Native ms Lptb2fg P. aeruginosa Lptb2fgc 
UnknownConjuring up a ghost: structural and functional characterization of FhuF, a ferric siderophore reductase from E. coli.
Not available
S-EPMC8068687 | biostudies-literature
UnknownCarbon Dioxide Hydrogenation to Formate Catalyzed by a Bench-Stable, Non-Pincer-Type Mn(I) Alkylcarbonyl Complex.
Not available
S-EPMC8155569 | biostudies-literature
UnknownThe ants of the genus Rhopalothrix Mayr, 1870 (Hymenoptera, Formicidae, Myrmicinae) in Colombia.
Not available
S-EPMC10880107 | biostudies-literature
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