Sort   by:  
 Page size 
ProteomicsStructural snapshots of Pseudomonas aeruginosa LptB2FG and LptB2FGC reveal insights into lipopolysaccharide recognition and transport - native mass spectrometry data
Gram-negative bacteria are intrinsically resistant to many antibiotics because of densely packed lipopolysaccharides (LPS) in the outer leaflet of their outer membrane (OM), which acts as a highly effective barrier towards the spontaneous permeation of toxic molecules, including antibiotics. LPS are...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2025-10-22 | PXD069660 | Pride
Lipopolysaccharide Lps Native ms Lptb2fg P. aeruginosa Lptb2fgc 
UnknownCombining Mutations That Inhibit Two Distinct Steps of the ATP Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers Transport.
Not available
S-EPMC6703430 | biostudies-literature
UnknownStructural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Not available
S-EPMC6532066 | biostudies-literature
UnknownConformational Plasticity of LptC Regulates Lipopolysaccharide Transport by the LptB<sub>2</sub>FGC Complex.
Not available
S-EPMC12498426 | biostudies-literature
UnknownA novel antibiotic class targeting the lipopolysaccharide transporter.
Not available
S-EPMC10794144 | biostudies-literature
UnknownStructural snapshots of Pseudomonas aeruginosa LptB<sub>2</sub>FG and LptB<sub>2</sub>FGC reveal insights into lipopolysaccharide recognition and transport.
Not available
S-EPMC12738788 | biostudies-literature
UnknownLipopolysaccharide transport involves long-range coupling between cytoplasmic and periplasmic domains of the LptB2FGC extractor.
Not available
S-EPMC8095461 | biostudies-literature
UnknownSuppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide.
Not available
S-EPMC9972910 | biostudies-literature
UnknownThanatin targets the intermembrane protein complex required for lipopolysaccharide transport in Escherichia coli.
Not available
S-EPMC6235536 | biostudies-literature
ProteomicsThanatin Targets the Inter-Membrane Protein Complex Required for Lipopolysaccharide Transport in Escherichia coli
With the increasing resistance of many Gram-negative bacteria to existing classes of antibiotics, identifying new paradigms in antimicrobial discovery is an important research priority. Of special interest here are the proteins required for the biogenesis of the symmetric Gram-negative bacterial out...
ORGANISM(S): Escherichia coli 
2019-01-23 | PXD010988 | Pride
Photoaffinity labeling Thermo q-exactive plus Macrocyclic peptidomimetic antibiotics Interaction mapping Lpt complex Photo crosslinking Gram-negative eskape pathogens Molecular mode of action E.coli Dda Ompta (outer membrane-targeting antibiotics) Lc-ms/ms 
Sort   by:  
 Page size