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ProteomicsReduction in synaptic vesicle proteins but increase in proteins involved in basic cell function in cerebral cortices without the endosomal SNARE proteins Vti1a and Vti1b
Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which Vti1a and Vti1b are involved. ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-31 | PXD066845 | Pride
Membrane traffic Snare Endosome Neurodegeneration Proteome 
ProteomicsVittrup Man – the life-history of a genetic foreigner in Neolithic Denmark
The deadly maltreated body of Vittrup Man was deposited in a Danish bog, probably as part of a ritualised sacrifice. It happened between c. 3300 and 3100 cal years BC, i.e., during the period of the local farming-based Funnel Beaker Culture. In terms of skull morphological features he differs from t...
ORGANISM(S): Homo sapiens (Human) 
2024-02-16 | PXD044743 | Pride
Ancient dental calculus Funnel beaker culture Human dental calculus Denmark 
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